To Explore the Effects of Different Training Periods and Dietary Pattern on the Gut Microbiota, Metabolites and Protein Expression Levels of Strength and Endurance Athletes and to Find Relevant Biological Indicators.

NCT04710667 | Unknown

• 1 other identifier: IRB-19-039-B1
• Study Type: observational
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The gastrointestinal tract contains hundreds of millions of microorganisms, collectively called the intestinal flora, which plays an important role in the health of the host. Many studies have also confirmed that the composition and function of the intestinal flora can be changed through the training chain. Changes in the composition of intestinal microbes can affect exercise performance, energy metabolism, oxidative stress, immune function, inflammation, and tissue repair. Therefore, maintaining a healthy gut microbial balance is essential for athletes' health, training, nutritional status, and athletic performance. This project intends to use metagenomics, proteomics, and metabolomics and other technologies to systematically explore the effects of different training periods and dietary interventions on the intestinal flora of muscle strength and endurance athletes. , Protein expression and the influence of metabolites. In the plan, explore the differences in the intestinal flora between muscle strength and endurance sports athletes during the preparation period, competition period, and transition period, and collect blood and feces to perform protein and metabolite molecular changes. It is hoped that through the smooth implementation of this research project, the research results can be applied to personalized diet planning, improve intestinal adaptability and the effectiveness of sports nutrition intervention, and then adjust athletes' status and improve sports performance to win the highest honor for the country in the arena.

Conditions

Athlete

Outcome Measures

Primary Outcomes (1)

• Differences in intestinal flora of athletes in sports during preparation, competition and transition periods

  asparate aminotransferase、alanine aminotransferase、albumin、blood urea nitrogen Creatinine、uric acid、total cholesterol、triacylglycerol、High-density lipoprotein、Low density lipoprotein、Free fatty acid、glucose、creatine kinase、gut microbiota

  2021/1/1-2021/2/28

Eligibility Criteria

• Age: 20 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Recruitment of 12 healthy muscle and endurance athletes from the National Sports University

You may qualify if:

• years old healthy muscle strength and endurance sports athletes

You may not qualify if:

• Exclude cardiovascular disease, hypertension, metabolic disease, asthma, or neuromuscular sports injuries within six months, etc.
• Exclude those who regularly take lactic acid bacteria-related foods for a long time
• Exclude students and related stakeholders under the guidance of the project host

Sponsors & Collaborators

• National Taiwan Sport University: lead

Study Sites (1)

National Taiwan Sport University

Taoyuan, 333, Taiwan

RECRUITING

Central Study Contacts

YuChih Lin

CONTACT

+886961546309; jarling217015@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 12, 2021
• First Posted: January 15, 2021
• Study Start: October 30, 2020
• Primary Completion: February 3, 2021
• Study Completion: February 3, 2021
• Last Updated: January 15, 2021

Record last verified: 2021-01

Locations

TW (1)