Latest Imaging SPECT System Evaluation Phase 1

NCT04704349 | Completed

• 1 other identifier: CHRO-2019-12
• Study Type: interventional
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

Monocentric study for the evaluation of a whole body CZT scintigraphy system.

Conditions

Rheumatic Disease; Neoplasms; Parathyroid Diseases; Pulmonary Embolism; Heart Diseases; Thyroid Diseases; Kidney Diseases; Dementia; Parkinsonian Disorders

Keywords

Gamma camera; whole body scan; scintigraphy

Outcome Measures

Primary Outcomes (1)

• Rate of images with a score greater than or equal to 4

  Rate of images obtaining a score greater than or equal to 4 in visual image quality analysis on a 5-point LIKERT scale.

  Day 0

Secondary Outcomes (1)

• collimator performance

  Day 0

Study Arms (1)

Scintigraphy acquisitions

EXPERIMENTAL

All patients will undergo scintigraphy on 2 distinct devices and the images obtained will be compared.

Radiation: Scintigraphy

Interventions

Scintigraphy RADIATION

The scintigraphy of the patients will be carried out on 2 distinct devices and the images obtained will be compared.

Scintigraphy acquisitions

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients referred to our Nuclear Medicine department for bone, cardiac, pulmonary, thyroid, parathyroid, renal or cerebral perfusion scintigraphy or to DaTSCAN.

You may not qualify if:

• Under 18 years old patients.
• Pregnant women or at risk of pregnancy.
• Patients under guardianship
• Painful patient (EVA\>4)
• Patients in whom a standard examination is not feasible (agitation).

Sponsors & Collaborators

• Centre Hospitalier Régional d'Orléans: lead

Study Sites (1)

CHR d'Orleans

Orléans, 45067, France

Location

Related Publications (9)

• Garcia EV, Faber TL, Esteves FP. Cardiac dedicated ultrafast SPECT cameras: new designs and clinical implications. J Nucl Med. 2011 Feb;52(2):210-7. doi: 10.2967/jnumed.110.081323. Epub 2011 Jan 13.

  PMID: 21233190 BACKGROUND

• Garcia EV. Are SPECT measurements of myocardial blood flow and flow reserve ready for clinical use? Eur J Nucl Med Mol Imaging. 2014 Dec;41(12):2291-3. doi: 10.1007/s00259-014-2924-2. No abstract available.

  PMID: 25311927 BACKGROUND

• Slomka PJ, Berman DS, Germano G. New cardiac cameras: single-photon emission CT and PET. Semin Nucl Med. 2014 Jul;44(4):232-51. doi: 10.1053/j.semnuclmed.2014.04.003.

  PMID: 24948149 BACKGROUND

• Bani Sadr A, Testart N, Tylski P, Scheiber C. Reduced Scan Time in 123I-FP-CIT SPECT Imaging Using a Large-Field Cadmium-Zinc-Telluride Camera. Clin Nucl Med. 2019 Jul;44(7):568-569. doi: 10.1097/RLU.0000000000002554.

  PMID: 30932983 BACKGROUND

• Salerno M, Beller GA. Noninvasive assessment of myocardial perfusion. Circ Cardiovasc Imaging. 2009 Sep;2(5):412-24. doi: 10.1161/CIRCIMAGING.109.854893. No abstract available.

  PMID: 19808630 BACKGROUND

• Mowatt G, Vale L, MacLeod A. Systematic review of the effectiveness of home versus hospital or satellite unit hemodialysis for people with end-stage renal failure. Int J Technol Assess Health Care. 2004 Summer;20(3):258-68. doi: 10.1017/s0266462304001060.

  PMID: 15446754 BACKGROUND

• Loong CY, Anagnostopoulos C. Diagnosis of coronary artery disease by radionuclide myocardial perfusion imaging. Heart. 2004 Aug;90 Suppl 5(Suppl 5):v2-9. doi: 10.1136/hrt.2003.013581. No abstract available.

  PMID: 15254003 BACKGROUND

• Roach PJ, Gradinscak DJ, Schembri GP, Bailey EA, Willowson KP, Bailey DL. SPECT/CT in V/Q scanning. Semin Nucl Med. 2010 Nov;40(6):455-66. doi: 10.1053/j.semnuclmed.2010.07.005.

  PMID: 20920635 BACKGROUND

• Valotassiou V, Malamitsi J, Papatriantafyllou J, Dardiotis E, Tsougos I, Psimadas D, Alexiou S, Hadjigeorgiou G, Georgoulias P. SPECT and PET imaging in Alzheimer's disease. Ann Nucl Med. 2018 Nov;32(9):583-593. doi: 10.1007/s12149-018-1292-6. Epub 2018 Aug 20.

  PMID: 30128693 BACKGROUND

MeSH Terms

Conditions

Rheumatic Diseases; Neoplasms; Parathyroid Diseases; Pulmonary Embolism; Heart Diseases; Thyroid Diseases; Kidney Diseases; Dementia; Parkinsonian Disorders

Condition Hierarchy (Ancestors)

Musculoskeletal Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Endocrine System Diseases; Lung Diseases; Respiratory Tract Diseases; Embolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders; Basal Ganglia Diseases; Movement Disorders

Study Officials

• Gilles METRARD, Dr

  CHR Orléans

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: All patients will undergo scintigraphy on 2 distinct devices and the images obtained will be compared.

Study Record Dates

• First Submitted: January 6, 2021
• First Posted: January 11, 2021
• Study Start: October 5, 2020
• Primary Completion: January 27, 2021
• Study Completion: January 27, 2021
• Last Updated: November 3, 2021

Record last verified: 2021-11

Locations

FR (1)