NCT04700293

Brief Summary

To evaluate tolerance and acceptability of 'AMSTERDAM' in patients requiring supplementary oral nutritional support compared with currently available alternatives.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2019

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

January 5, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 7, 2021

Completed
Last Updated

January 7, 2021

Status Verified

January 1, 2021

Enrollment Period

9 months

First QC Date

January 5, 2021

Last Update Submit

January 6, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Gastro-Intestinal Tolerance when consuming AYMES AMSTERDAM

    To assess gastro-intestinal tolerance of 'AMSTERDAM' in patients in the community requiring oral nutritional supplementation. Monitoring includes recording the number of any GI complaints via a daily diary.

    7 days

Secondary Outcomes (1)

  • Acceptability and Palatability of Consuming the Nutritional Supplement: questionnaire

    7 days

Study Arms (1)

AYMES AMSTERDAM

EXPERIMENTAL

Patients established on an oral nutritional supplement (ONS), requiring nutritional supplementation of at least 300kcal/day will be changed onto an equivalent prescription of AYMES 'AMSTERDAM' for a period of \> 7 days.

Dietary Supplement: AYMES AMSTERDAM

Interventions

AYMES AMSTERDAMDIETARY_SUPPLEMENT

AYMES AMSTERDAM is a Food for Special Medical Purposes (FSMP) and must, therefore, be used under medical supervision. It is not designed as a sole source of nutrition.

AYMES AMSTERDAM

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male and female participants.
  • ≥ 18 years of age.
  • Participants of the intended target group (e.g. MUST score ≥ 1) with an anticipated period of nutritional support ≥ 7 days.
  • Patient is able and willing to provide written informed consent.

You may not qualify if:

  • Participants with medical or dietary contraindication to any feed ingredients.
  • Participants requiring sole enteral tube feeding or parenteral nutrition.
  • Participants with significant renal (requiring dialysis) or hepatic impairment (e.g. hepatitis.)
  • Participants with dysphagia requiring levels 1, 2, 3 or 4 thickened fluids.
  • Participants with uncontrolled inflammatory bowel disease or previous bowel resection with ongoing gastrointestinal symptoms.
  • Participants for whom the investigator has concerns regarding the ability or willingness of the patient and or carer to comply with protocol requirements.
  • Participation in any other studies involving investigational or marketed products concomitantly or within 2 weeks prior to entry into the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AYMES International Ltd.

Haywards Heath, RH16 9PL, United Kingdom

Location

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition DisordersNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 5, 2021

First Posted

January 7, 2021

Study Start

March 1, 2019

Primary Completion

December 1, 2019

Study Completion

December 1, 2019

Last Updated

January 7, 2021

Record last verified: 2021-01

Data Sharing

IPD Sharing
Will not share

Locations