Trials Sponsors Conditions Drugs Pricing

Conditions

Alveolar Bone Loss Platelet Rich Plasma

Keywords

Dental implant, Cone Beam Computerized Tomography (CBCT).

Outcome Measures

Primary Outcomes (1)

Measurement of bone loss at baseline (12 weeks) and later at 26weeks
Measurement at mesial in mm
Baseline -before functional loading at 12 weeks & at 26 weeks- after functional loading to assess changes in marginal bone loss in sagittal view using CBCT

Secondary Outcomes (1)

Measurement of bone loss at baseline (12 weeks) and later at 26weeks
Baseline -before functional loading at 12 weeks & at 26 weeks- after functional loading to assess changes in marginal bone loss in sagittal view using CBCT

Other Outcomes (1)

Bone Mineral Density
Baseline -before functional loading at 12 weeks & at 26 weeks- after functional loading to assess changes in marginal bone loss in sagittal view using CBCT

Study Arms (2)

Control Group

NO INTERVENTION

Dental implant was placed in these patients following full protocol of immediate implant placement.

PRP Group

EXPERIMENTAL

In this group Platelet Rich Plasma (PRP) was injected in soft tissue over surgical site.

Biological: PRP injectionDevice: Automated blood cell separator to extract PRP

Interventions

PRP injectionBiological

PRP was prepared using patient's blood and mixed with saline or mixture of calcium chloride and thrombin to form a liquid solution; in order to inject at the surgical site after placement of implant.

Also known as: Platelet Rich Plasma injection

PRP Group

Automated blood cell separator to extract PRPDevice

Blood was withdrawn from antecubital vein and mixed with anticoagulant. Blood sample was then centrifuged to obtain platelet rich plasma which was injected at surgical site after implant placement.

Eligibility Criteria

Age20 Years - 50 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

patients maintaining good oral hygiene, having adequate bone quantity at the implant site, uneventful extraction

You may not qualify if:

Sponsors & Collaborators

CMH Lahore Medical College and Institute of Dentistry
Otherlead

Study Sites (1)

Institute of Dentistry; CMH Lahore Medical College

Lahore, Punjab Province, Pakistan

Related Publications (2)

Boora P, Rathee M, Bhoria M. Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement: A Randomized Controlled Trial. J Clin Diagn Res. 2015 Apr;9(4):ZC18-21. doi: 10.7860/JCDR/2015/12636.5788. Epub 2015 Apr 1.
PMID: 26023636RESULT
Khan AS, Zaheer N, Zaigham AM, Shahbaz M, Zaheer U, Alam MK. Effect of Platelet-Rich Plasma on Bone Healing in Immediate Implants Analyzed by Cone Beam Computerized Tomography: A Randomized Controlled Trial. Biomed Res Int. 2021 Mar 13;2021:6685991. doi: 10.1155/2021/6685991. eCollection 2021.
PMID: 33791377DERIVED

MeSH Terms

Conditions

Alveolar Bone Loss

Condition Hierarchy (Ancestors)

Bone ResorptionBone DiseasesMusculoskeletal DiseasesPeriodontal AtrophyPeriodontal DiseasesMouth DiseasesStomatognathic Diseases

Study Officials

Aleshba Saba khan, BDS; FCPS
Institute of Dentistry; CMH Lahore Medical College
PRINCIPAL INVESTIGATOR
Naauman Zaheer, BDS; PhD
Institute of Dentistry; CMH Lahore Medical College
PRINCIPAL INVESTIGATOR
Abdul Mueed Zaigham, BDS; FCPS
Institute of Dentistry; CMH Lahore Medical College
STUDY CHAIR
Maliha Shahbaz, BDS; MPhil
Oral Biology Department; Rashid Latif Dental College, Lahore
STUDY DIRECTOR

Enrollment

12 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Professor & Head Prosthodontics Department

Study Record Dates

First Submitted

November 14, 2020

First Posted

December 3, 2020

Study Start

October 2, 2017

Actual (reported)

Bone Healing in Immediate Dental Implants

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Other Outcomes (1)

Study Arms (2)

Control Group

PRP Group

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (2)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Other Outcomes (1)

Study Arms (2)

Control Group

PRP Group

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (2)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Data Sharing

Source record

Locations