NCT04633135

Brief Summary

REACCTING (Research on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana) is an interdisciplinary randomized cookstove intervention study in the Kassena-Nankana District of Northern Ghana. The study tests two types of biomass burning stoves that have the potential to meet local cooking needs and represent different "rungs" in the cookstove technology ladder: a locally-made, low-tech Gyapa rocket stove and the imported, highly efficient Philips gasifier stove. Intervention households were randomized into four different groups, three of which received different combinations of two improved stoves, while the fourth group serves as a control for the duration of the study. Diverse measurements assess different points along the causal chain linking the intervention to final outcomes of interest. The investigators assess stove use and cooking behavior, cooking emissions, household air pollution and personal exposure, health burden, and local to regional air quality. Integrated analysis and modeling will tackle a range of interdisciplinary science questions, including examining ambient exposures among the regional population, assessing how those exposures might change with different technologies and behaviors, and estimating the comparative impact of local behavior and technological changes versus regional climate variability and change on local air quality and health outcomes.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2012

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2016

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2017

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

September 14, 2020

Completed
2 months until next milestone

First Posted

Study publicly available on registry

November 18, 2020

Completed
Last Updated

November 18, 2020

Status Verified

November 1, 2020

Enrollment Period

5 years

First QC Date

September 14, 2020

Last Update Submit

November 11, 2020

Conditions

Outcome Measures

Primary Outcomes (16)

  • Health (Biomarkers of inflammation)

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

    At baseline

  • Health (Biomarkers of inflammation)

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

    At 6 months

  • Health (Biomarkers of inflammation)

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

    At 12 months

  • Health (Biomarkers of inflammation)

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

    At 18 months

  • Height

    Height of participants

    At baseline

  • Height

    Height of participants

    At 6 months

  • Height

    Height of participants

    At 12 months

  • Height

    Height of participants

    At 18 months

  • Weight

    Weight of participants

    At baseline

  • Weight

    Weight of participants

    At 6 months

  • Weight

    Weight of participants

    At 12 months

  • Weight

    Weight of participants

    At 18 months

  • Mid-arm circumference

    Measurement of mid-upper arm circumference of participants

    At baseline

  • Mid-arm circumference

    Measurement of mid-upper arm circumference of participants

    At 6 months

  • Mid-arm circumference

    Measurement of mid-upper arm circumference of participants

    At 12 months

  • Mid-arm circumference

    Measurement of mid-upper arm circumference of participants

    At 18 months

Secondary Outcomes (9)

  • Personal exposure to fine particulate matter (PM2.5)

    48 hour deployment periods

  • Personal exposure to carbon monoxide (CO)

    48 hour deployment periods

  • Kitchen area concentrations of carbon monoxide (CO)

    48 hour deployment periods

  • Kitchen area concentrations of fine particulate matter (PM2.5)

    48 hour deployment periods

  • Self-reported stove usage

    At baseline

  • +4 more secondary outcomes

Study Arms (4)

Control

NO INTERVENTION

Households enrolled in the control arm of the study did not receive either improved cookstove

Gyapa/Gyapa

EXPERIMENTAL

Households enrolled in the Gyapa/Gyapa arm of the study received two Gyapa stoves for free

Device: Gyapa stove

Gyapa/Philips

EXPERIMENTAL

Households enrolled in the Gyapa/Philips arm of the study received one Gyapa stove and one Philips stove for free

Device: Philips stoveDevice: Gyapa stove

Philips/Philips

EXPERIMENTAL

Households enrolled in the Philips/Philips arm of the study received two Philips stoves for free

Device: Philips stove

Interventions

Philips Smokeless stove HD4012LS

Also known as: Gasifier stove
Gyapa/PhilipsPhilips/Philips

Wood stove made in Ghana

Also known as: Rocket stove
Gyapa/GyapaGyapa/Philips

Eligibility Criteria

Age0 Years - 55 Years
Sexall(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Individual Participants:
  • Classified as "rural"
  • Uses biofuel as main cooking fuel source (firewood, animal waste, crop residue/sawdust)
  • Uses borehole as main water source (to facilitate social network analysis linking household's knowledge and attitudes toward stoves to experience of social contacts);
  • Does not have electricity (to permit possible addition of lighting intervention at a later date);
  • Has a woman in household aged 18-55 and at least one child under five (since women and children are the most vulnerable to cookstove smoke and are thus the main focus of our health measures).
  • Clusters:
  • No more than 25% classified as urban
  • Accessible year-round (determined by field staff)
  • Having at least 10 eligible households (in line with the participant criteria above)

You may not qualify if:

  • Household could not be located
  • Household declined to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Dickinson KL, Kanyomse E, Piedrahita R, Coffey E, Rivera IJ, Adoctor J, Alirigia R, Muvandimwe D, Dove M, Dukic V, Hayden MH, Diaz-Sanchez D, Abisiba AV, Anaseba D, Hagar Y, Masson N, Monaghan A, Titiati A, Steinhoff DF, Hsu YY, Kaspar R, Brooks B, Hodgson A, Hannigan M, Oduro AR, Wiedinmyer C. Research on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana (REACCTING): study rationale and protocol. BMC Public Health. 2015 Feb 12;15:126. doi: 10.1186/s12889-015-1414-1.

    PMID: 25885780BACKGROUND
  • Abdo M, Kanyomse E, Alirigia R, Coffey ER, Piedrahita R, Diaz-Sanchez D, Hagar Y, Naumenko DJ, Wiedinmyer C, Hannigan MP, Oduro AR, Dickinson KL. Health impacts of a randomized biomass cookstove intervention in northern Ghana. BMC Public Health. 2021 Dec 4;21(1):2211. doi: 10.1186/s12889-021-12164-y.

MeSH Terms

Conditions

Inflammation

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Model Details: There were 4 groups, 3 intervention and 1 control, all operating over the same period.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle Investigator

Study Record Dates

First Submitted

September 14, 2020

First Posted

November 18, 2020

Study Start

January 1, 2012

Primary Completion

December 31, 2016

Study Completion

December 31, 2017

Last Updated

November 18, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

De-identified data are available upon request.