Central Venous Pressure Monitoring and Prognosis of High-risk Operating Patients

NCT04596332 | Completed

• 1 other identifier: K2018-09-006
• Study Type: observational
• Target: 196
• Locations: 0 countries
• Sites: N/A

Brief Summary

While central venous pressure measurement is used to guide fluid management in high risk surgical patients during perioperative period, the relationship between the value of central venous pressure and organ dysfunction and prognosis of high-risk operating patients is unknow. In this study, we conducted a retrospective study of the relationship between the initial levels of CVP with organ dysfunction, the severity of illness, the length of ICU stay, and prognosis of critically ill patients.

Conditions

Central Venous Pressure

Keywords

perioperative; central venous pressure; fluid management; acute renal injury

Outcome Measures

Primary Outcomes (1)

• Primary Outcome

  28-day mortality, length of stay in intensive care unit and hospitalization, surgical complications

  28-day

Secondary Outcomes (1)

• Secondary Outcome

  1-day

Study Arms (3)

Group A

Patients with the initial central venous pressure(CVP1) \<8 mm Hg

Other: no intervention measures

Group B

Patients with 8≤CVP1≤12mm Hg

Other: no intervention measures

Group C

Patients with CVP1\>12 mm Hg

Other: no intervention measures

Interventions

no intervention measures OTHER

Because this study was a retrospective study, no intervention measures were implemented for the patients enrolled.

Group A; Group B; Group C

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This is a single-center, retrospective, observational study enrolled 196 patients undergoing high-risk surgery who admitted to surgical intensive care unit(SICU) directly after operation from Feb 1,2014 to Mar 31,2018.

You may qualify if:

• Age ≥18 years.⑵ All patients undergoing surgery and admitted to our intensive care unit (ICU) directly after surgery were enrolled into the respective study.⑶ They stayed in the ICU more than 48 hours with central venous pressure monitored for more than 48 hours.

You may not qualify if:

• Patients who were in pregnancy. ⑵Older than 80 years. ⑶Underwent cardiac surgery or had chronic kidney disease.

Sponsors & Collaborators

• Fujian Provincial Hospital: lead

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• Jiafang Wu, M.D.

  Department of Critical Care Medicine, Fujian Provincial Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Target Duration: 28 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Department of Critical Care Medicine, Fujian Provincial Hospital

Study Record Dates

• First Submitted: October 15, 2020
• First Posted: October 22, 2020
• Study Start: February 1, 2014
• Primary Completion: March 31, 2018
• Study Completion: March 30, 2020
• Last Updated: October 22, 2020

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share