NCT01099254

Brief Summary

The Trendelenburg position is used to distend the central veins, improving both success and safety of vascular cannulation. The purpose of this study is to measure the cross-sectional area of the internal jugular vein (IJV) in three different positions, using surface ultrasound.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2007

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2007

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2010

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

March 29, 2010

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 6, 2010

Completed
Last Updated

November 15, 2023

Status Verified

November 1, 2023

Enrollment Period

2.6 years

First QC Date

March 29, 2010

Last Update Submit

November 14, 2023

Conditions

Keywords

CVPUSTrendelenburg positionUltrasoundHead Down Tilt

Outcome Measures

Primary Outcomes (1)

  • Effect of trendelenburg and reverse trendelenburg position on the cross sectional area of the internal jugular vein

    There will be substantial anatomic variation in venous size. Further, Trendelenburg positioning will have little impact on venous cross-sectional area in most subjects when compared with supine.

    At time of data collection: physiologic study

Eligibility Criteria

Age18 Years - 120 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients admitted to Intensive care unit.

You may qualify if:

  • adult medical or surgical ICU patients who have preexisting central venous (jugular/subclavian only) catheters.

You may not qualify if:

  • subjects with only a femoral venous catheter.
  • subjects whose CVP measurement by the indwelling catheter exceeds 20cm of water.
  • subjects younger than 18 years old.
  • inability to obtain informed consent from the subject or the subjects authorized representative.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Iowa

Iowa City, Iowa, 52246, United States

Location

Related Publications (3)

  • Bazaral M, Harlan S. Ultrasonographic anatomy of the internal jugular vein relevant to percutaneous cannulation. Crit Care Med. 1981 Apr;9(4):307-10. doi: 10.1097/00003246-198104000-00004.

    PMID: 7214938BACKGROUND
  • Vinayak AG, Levitt J, Gehlbach B, Pohlman AS, Hall JB, Kress JP. Usefulness of the external jugular vein examination in detecting abnormal central venous pressure in critically ill patients. Arch Intern Med. 2006 Oct 23;166(19):2132-7. doi: 10.1001/archinte.166.19.2132.

    PMID: 17060544BACKGROUND
  • Nassar B, Deol GRS, Ashby A, Collett N, Schmidt GA. Trendelenburg position does not increase cross-sectional area of the internal jugular vein predictably. Chest. 2013 Jul;144(1):177-182. doi: 10.1378/chest.11-2462.

Study Officials

  • Gregory A Schmidt, mD

    Roy J. & Lucille A. Carver College of Medicine, University of Iowa

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 29, 2010

First Posted

April 6, 2010

Study Start

August 1, 2007

Primary Completion

March 1, 2010

Study Completion

March 1, 2010

Last Updated

November 15, 2023

Record last verified: 2023-11

Locations