Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study

NCT04587310 | Completed

• 1 other identifier: IJS-S-20-02914
• Study Type: observational
• Target: 92
• Locations: 0 countries
• Sites: N/A

Brief Summary

Introduction Laparoscopic Sleeve Gastrectomy (LSG) is one of the most prevalent approaches to tackle obesity and its co-morbidities. The main complication following the LSG is Gastro-esophageal reflux disease (GERD), with most patients developing worsening symptoms of GERD, and a small number progressing to Barrett's esophagus. This retrospective analysis aims to assess the rate of GERD pre- and post- LSG as well as the rate of progression to Barrett's. Methods Data was collected from 1639 patients. 92 patients fit our inclusion criteria. Data was then analyzed and summarized against similar literature

Conditions

Barrett Esophagus

Outcome Measures

Primary Outcomes (1)

• endoscopy performed on patients

  endoscopy will be performed on patients 5 years after undergoing sleeve gastrectomy due to the fact that sleeve tends to lead to reflux which causes dysplasia of esophageal cells, which eventually can lead to barrett's esophagus and cancer.

  5 years

Interventions

Laparoscopic Sleeve Gastrectomy DIAGNOSTIC_TEST

bariatric surgery

Eligibility Criteria

• Age: 24 Years - 36 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Data was collected from 1639 patients. 92 patients fit our inclusion criteria. Data was then analyzed and summarized against similar literature

You may qualify if:

• patients eligible to sleeve gastrectomy that had an EGD pre and 5 years post-op

You may not qualify if:

• missing or implausible data, had multiple surgeries, and suffered from the common post-sleeve complications, such as leaks, strictures and hiatal hernias

Sponsors & Collaborators

• Eliana Al Haddad: lead

MeSH Terms

Conditions

Barrett Esophagus

Condition Hierarchy (Ancestors)

Precancerous Conditions; Neoplasms; Esophageal Diseases; Gastrointestinal Diseases; Digestive System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: post-doc research fellow

Study Record Dates

• First Submitted: October 2, 2020
• First Posted: October 14, 2020
• Study Start: October 1, 2008
• Primary Completion: October 1, 2013
• Study Completion: September 20, 2020
• Last Updated: October 14, 2020

Record last verified: 2020-10