Barrett's Esophagus in Patients with GERD

NCT06897540 | Not Yet Recruiting

• 1 other identifier: Barrett's Esophagus
• Study Type: interventional
• Target: 70
• Locations: 0 countries
• Sites: N/A

Brief Summary

To assess the prevalence and characteristics of BE in patients suffering of chronic GERD symptoms

Conditions

Barrett Esophagus

Outcome Measures

Primary Outcomes (1)

• To assess the prevalence and characteristics of BE in patients suffering of chronic GERD symptoms.

  To assess the prevalence and characteristics of BE in patients suffering of chronic GERD symptoms. To evaluate demographic and clinical risk factors associated with BE in GERD patients. To assess the clinical features of GERD in patients who develop BE. To investigate the diagnostic methods used to detect BE in clinical settings. To assess the relationship between chronicity of GERD and development of BE.

  Assessment of patients with GERD take about 2 weeks

Study Arms (1)

Patients with GERD

OTHER

Screening for Barrett's esophagus in patients with GERD by upper endoscopy

Device: Upper endoscopy

Interventions

Upper endoscopy DEVICE

View mucosa of esophagus with upper endoscope

Patients with GERD

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults diagnosed with GERD based on clinical symptoms and/or 24-hour pH monitoring or esophageal manometry.
• Patients willing to undergo endoscopic examination

You may not qualify if:

• Patients with other esophageal diseases, such as eosinophilic esophagitis, infections, or motility disorders.
• Patients who are unable to consent or participate in the study

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Barrett Esophagus

Interventions

Gastroscopy

Condition Hierarchy (Ancestors)

Precancerous Conditions; Neoplasms; Esophageal Diseases; Gastrointestinal Diseases; Digestive System Diseases

Intervention Hierarchy (Ancestors)

Endoscopy, Gastrointestinal; Endoscopy, Digestive System; Diagnostic Techniques, Digestive System; Diagnostic Techniques and Procedures; Diagnosis; Endoscopy; Diagnostic Techniques, Surgical; Digestive System Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor at Assiut University Hospitals

Study Record Dates

• First Submitted: March 17, 2025
• First Posted: March 27, 2025
• Study Start: April 1, 2025
• Primary Completion: March 31, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: March 27, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share