Key Insights

Highlights

Success Rate

85% trial completion

Published Results

22 trials with published results (15%)

Research Maturity

61 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.6%

11 terminated out of 144 trials

Success Rate

84.7%

-1.8% vs benchmark

Late-Stage Pipeline

1%

2 trials in Phase 3/4

Results Transparency

36%

22 of 61 completed with results

Key Signals

22 with results85% success11 terminated

Data Visualizations

Phase Distribution

93Total
Not Applicable (74)
Early P 1 (2)
P 1 (6)
P 2 (9)
P 3 (1)
P 4 (1)

Trial Status

Completed61
Recruiting24
Unknown22
Terminated11
Active Not Recruiting10
Enrolling By Invitation7

Trial Success Rate

84.7%

Benchmark: 86.5%

Based on 61 completed trials

Clinical Trials (144)

Showing 20 of 20 trials
NCT07212491Enrolling By InvitationPrimary

Minimally Invasive Molecular Approaches for the Detection of Barrett's Esophagus- High Grade Dysplasia and Esophageal Adenocarcinoma

NCT05216133Enrolling By Invitation

Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)

NCT02521285Phase 2Active Not RecruitingPrimary

Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation

NCT07206589Not ApplicableNot Yet RecruitingPrimary

Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C Trial

NCT04939051Phase 2RecruitingPrimary

Obeticholic Acid for Prevention in Barrett's Esophagus

NCT06732388Phase 2Not Yet RecruitingPrimary

Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

NCT07126535Recruiting

Impact of RFA on Esophageal Distensibility and Mucosal Impedance

NCT07490340Active Not RecruitingPrimary

Trans-Oral Sampling as an Alternative Surveillance of Barrett's Esophagus Pilot

NCT04312633RecruitingPrimary

Clinical Utility of WATS3D: A 5-Year Prospective Study

NCT06803927RecruitingPrimary

Non-Endoscopic Detection of Barrett's Esophagus Using Methylation Biomarkers on EndoSign® Cell Collection Device Samples

NCT07455422Not ApplicableNot Yet RecruitingPrimary

A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer

NCT03554356Not ApplicableActive Not RecruitingPrimary

Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)

NCT06346054Not ApplicableRecruiting

Molecular Assessment for Gastro-Esophageal Cancer

NCT05468008Recruiting

Endoscopic Submucosal Dissection (ESD)

NCT03961945Not ApplicableRecruitingPrimary

Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma

NCT01618643CompletedPrimary

Aceto-whitening in the Assessment of Gastrointestinal Neoplasia

NCT03853772Enrolling By Invitation

The Johns Hopkins Heartburn Center Registry

NCT00431756Active Not RecruitingPrimary

Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus

NCT05107219Phase 1Active Not RecruitingPrimary

GCC Agonist Signal in the Small Intestine

NCT06071845Not ApplicableRecruitingPrimary

Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

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