User-friendly HIV Testing and Counseling Services

NCT04585165 | Unknown

• 1 other identifier: Napneung-2
• Study Type: observational
• Target: 3,000
• Locations: 1 country
• Sites: 6

Brief Summary

Multicenter cohort study of individuals reporting behavioral risks of HIV acquisition, recruited among those presenting for testing for HIV and other sexually transmitted infections. Overarching goal: to study factors associated with uptake of HIV prevention and (re)testing services in medium-sized cities in Thailand. Primary objective: To estimate the incidence of HIV and other sexually transmitted infections (syphilis, chronic hepatitis B and C) among individuals presenting for retesting. Secondary objectives:

• To evaluate the uptake of pre-exposure prophylaxis
• To assess retention in the study
• To evaluate client HIV knowledge
• To describe HIV prevalence and characteristics of individuals newly diagnosed with HIV
• To describe characteristics of individuals at risk of HIV infection
• To assess the quality of the testing and referral services.

Conditions

HIV Infections; Sexually Transmitted Infection; Hepatitis B, Chronic; Hepatitis C

Keywords

HIV; Testing; Self-testing; Retesting; Early diagnosis; Counseling; Computer; Reminder; Short message service; Pre-exposure prophylaxis

Outcome Measures

Primary Outcomes (1)

• HIV incidence

  HIV incidence

  Through study completion, an average of 3 years

Secondary Outcomes (3)

• Participants initiating pre-exposure prophylaxis

  Through study completion, an average of 3 years

• Retention

  Through study completion, an average of 3 years

• HIV knowledge

  Through study completion, an average of 3 years

Study Arms (1)

Risk of HIV acquisition

Individuals reporting behavioral risk of HIV acquisition.

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals requesting a test for HIV and sexually transmitted infections

You may qualify if:

• Aged 15 years or more
• Willing to be tested for HIV and other sexually transmitted infections
• Able to understand the study and its procedures

Sponsors & Collaborators

• Institut de Recherche pour le Developpement: lead
• Expertise France-L'Initiative: collaborator
• French National Research Institute for Sustainable Development (IRD): collaborator

Study Sites (6)

STIs Clinic of the Office of Disease Prevention and Control Region 1

Chiang Mai, 50100, Thailand

RECRUITING

Clinical Service Center, Faculty of Associated Medical Sciences, Chiang Mai University

Chiang Mai, 50200, Thailand

RECRUITING

MAP Foundation

Chiang Mai, Thailand

RECRUITING

Chiang Rai Obstetrics Clinic

Chiang Rai, 57000, Thailand

RECRUITING

Phayao Hospital

Phayao, 56000, Thailand

NOT YET RECRUITING

University of Phayao Medical Center and Hospital

Phayao, 56000, Thailand

RECRUITING

Related Publications (2)

• Salvadori N, Decker L, Ngo-Giang-Huong N, Mary JY, Chevret S, Arunothong S, Adam P, Khamduang W, Samleerat T, Luangsook P, Suksa-Ardphasu V, Achalapong J, Rouzioux C, Sirirungsi W, Jourdain G. Impact of Counseling Methods on HIV Retesting Uptake in At-Risk Individuals: A Randomized Controlled Study. AIDS Behav. 2020 May;24(5):1505-1516. doi: 10.1007/s10461-019-02695-2.

  PMID: 31605294 BACKGROUND

• Salvadori N, Adam P, Mary JY, Decker L, Sabin L, Chevret S, Arunothong S, Khamduang W, Luangsook P, Suksa-Ardphasu V, Achalapong J, Rouzioux C, Sirirungsi W, Ngo-Giang-Huong N, Jourdain G. Appointment reminders to increase uptake of HIV retesting by at-risk individuals: a randomized controlled study in Thailand. J Int AIDS Soc. 2020 Apr;23(4):e25478. doi: 10.1002/jia2.25478.

  PMID: 32294318 BACKGROUND

Related Links

• Presentation for potential participants

Biospecimen

Retention: SAMPLES WITH DNA

Plasma from remaining blood sample

MeSH Terms

Conditions

HIV Infections; Sexually Transmitted Diseases; Hepatitis B, Chronic; Hepatitis C; Disease

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Hepatitis B; Hepadnaviridae Infections; DNA Virus Infections; Hepatitis, Viral, Human; Hepatitis, Chronic; Hepatitis; Liver Diseases; Digestive System Diseases; Chronic Disease; Flaviviridae Infections

Study Officials

• Gonzague Jourdain, MD, PhD

  Chiang Mai University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Gonzague Jourdain, MD, PhD

CONTACT

+66 5324 0910; Gonzague.Jourdain@phpt.org

Nicolas Salvadori, PhD

CONTACT

+66 5324 0910; Nicolas.Salvadori@phpt.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Researcher

Study Record Dates

• First Submitted: April 27, 2020
• First Posted: October 14, 2020
• Study Start: October 19, 2020
• Primary Completion: September 1, 2024
• Study Completion: December 1, 2024
• Last Updated: October 31, 2023

Record last verified: 2023-10

Locations

TH (6)