Key Insights

Highlights

Success Rate

86% trial completion

Published Results

55 trials with published results (21%)

Research Maturity

139 completed trials (53% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

8.4%

22 terminated out of 262 trials

Success Rate

86.3%

-0.2% vs benchmark

Late-Stage Pipeline

36%

95 trials in Phase 3/4

Results Transparency

40%

55 of 139 completed with results

Key Signals

55 with results86% success22 terminated

Data Visualizations

Phase Distribution

195Total
Not Applicable (18)
Early P 1 (3)
P 1 (36)
P 2 (43)
P 3 (26)
P 4 (69)

Trial Status

Completed139
Unknown59
Terminated22
Recruiting15
Active Not Recruiting10
Withdrawn9

Trial Success Rate

86.3%

Benchmark: 86.5%

Based on 139 completed trials

Clinical Trials (262)

Showing 20 of 20 trials
NCT07555340Active Not RecruitingPrimary

A Real-World Study on the Efficacy and Safety of Pradefovir Mesylate Tablets in the Treatment of Chronic Hepatitis B

NCT07553767Early Phase 1Not Yet Recruiting

Efficacy and Safety of Pegylated Interferon Alpha-2β in Patients With Hepatitis B-related Hepatocellular Carcinoma After Radical Resection

NCT07298577Not ApplicableEnrolling By Invitation

Use of Gender, Age, Alfa-fetoprotein (AFP), and Des-gamma-carboxyprothrombin (PIVKA-II) or GAAD Score in Addition to Ultrasound for Surveillance of People At-risk for Developing Hepatocellular Carcinoma in Asia in Order to Detect Early Liver Cancer

NCT04856085Phase 2CompletedPrimary

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection

NCT07544121Not ApplicableNot Yet RecruitingPrimary

Effect of Babao Dan Capsule Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis

NCT07370207Phase 2RecruitingPrimary

Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region

NCT07491848RecruitingPrimary

Oral-Periodontal Evaluation and Assessment of Oral Fluid Biomarkers in Patients With Hepatitis B+D

NCT07481032Not ApplicableNot Yet Recruiting

Effect of Fufang Biejiaruangan Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis: A Multicenter, Randomized, Placebo-controlled Study

NCT07459426Not Yet RecruitingPrimary

Entecavir Resistance-Associated Mutations in Chronic HBV Patients in Turkey (STREAM Study)

NCT03866187Phase 1TerminatedPrimary

Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection

NCT05612581Phase 1CompletedPrimary

A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection

NCT02065336Phase 2TerminatedPrimary

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

NCT05276297Phase 2CompletedPrimary

A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapy

NCT05630807Phase 3Active Not Recruiting

Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 1)

NCT05630820Phase 3Active Not Recruiting

Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 2)

NCT04684914Phase 2TerminatedPrimary

HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)

NCT06550128Phase 2Active Not RecruitingPrimary

Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB).

NCT07242404Not Yet Recruiting

Comparison of a Handheld Elastography Device With iLivTouch in Chronic Liver Disease Patients

NCT04782375Phase 4Active Not RecruitingPrimary

Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis B

NCT06680232Phase 1RecruitingPrimary

Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B

Scroll to load more

Research Network

Activity Timeline