Impact of Chair Seat Height on the 1-Minute Sit to Stand Test Performance in Chronic Obstructive Pulmonary Disease

NCT04579055 | Completed DMC

• 1 other identifier: 2020-01677
• Study Type: interventional
• Target: 55
• Locations: 1 country
• Sites: 1

Brief Summary

The 1-minute sit to stand (1-min STS) test is a standardized test which is used to examine exercise capacity in patients with chronic obstructive pulmonary disease (COPD). The chair seat height used is standardized to 46-48 cm. Using a standard seat height for all patients - irrespective of their body height - may lead to invalid estimates of functional exercise capacity. The objective of this study is to assess whether there is a difference in repetitions during the 1-min STS test if the seat height is adjusted to 90° knee joint angle or the standard height chair of 46 cm is used.

Conditions

COPD; Chronic Obstructive Pulmonary Disease

Keywords

1-minute Sit to Stand Test; chair seat height

Outcome Measures

Primary Outcomes (1)

• Number of repetitions in the 1-min STS test

  difference in the amount of sit to stand repetitions in the 1-min STS test from a standard chair (46cm) or an individualized seat height chair of 90° knee joint angle

  During pulmonary rehabilitation, approximately 14 days

Secondary Outcomes (1)

• Sit to stand power index

  During pulmonary rehabilitation, approximately 14 days

Other Outcomes (6)

• Oxygen saturation

  During pulmonary rehabilitation, approximately 14 days

• Heart rate

  During pulmonary rehabilitation, approximately 14 days

• Ratings of perceived exertion

  During pulmonary rehabilitation, approximately 14 days

Study Arms (2)

1-min STS test: chair seat height adjusted to 90° knee flexion

EXPERIMENTAL

In this experimental condition, the patient performs the 1-minute sit to stand test on an individually adjusted seat height of 90° knee joint flexion.

Other: 1-min STS test: adjusted

1-min STS test: chair seat height standardized of 46cm

ACTIVE COMPARATOR

In this experimental condition, the patient performs the 1-minute sit to stand test on a standard height chair of 46cm.

Other: 1-min STS test: standardized

Interventions

1-min STS test: adjusted OTHER

Individually adjusted chair seat height of 90° knee joint flexion

1-min STS test: chair seat height adjusted to 90° knee flexion

1-min STS test: standardized OTHER

Standardized chair seat height of 46 cm

1-min STS test: chair seat height standardized of 46cm

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with diagnosed COPD according to a forced expiratory volume in 1s (FEV1) / forced vital capacity (FVC) ratio below the lower limit of normal

You may not qualify if:

• Patients who are not able to bend their knees while sitting on a standard chair (i.e., knee flexion less than 90°)
• Patients who are not able to understand the instructions of the 1-min STS test, either of language or cognitive reasons
• Patients who are unable to perform the STS test due to functional disability (i.e., being not able to rise from a chair without hand support), previous surgery, or pain according to the judgement of the responsible physician.
• Patients who did not sign the informed consent form

Sponsors & Collaborators

• Thomas Riegler: lead
• University of Zurich: collaborator

Study Sites (1)

Berner Reha Zentrum

Heiligenschwendi, Canton of Bern, 3625, Switzerland

Location

Related Publications (5)

• Crook S, Busching G, Schultz K, Lehbert N, Jelusic D, Keusch S, Wittmann M, Schuler M, Radtke T, Frey M, Turk A, Puhan MA, Frei A. A multicentre validation of the 1-min sit-to-stand test in patients with COPD. Eur Respir J. 2017 Mar 2;49(3):1601871. doi: 10.1183/13993003.01871-2016. Print 2017 Mar.

  PMID: 28254766 BACKGROUND

• Yoshioka S, Nagano A, Hay DC, Fukashiro S. Peak hip and knee joint moments during a sit-to-stand movement are invariant to the change of seat height within the range of low to normal seat height. Biomed Eng Online. 2014 Mar 12;13(1):27. doi: 10.1186/1475-925X-13-27.

  PMID: 24620992 BACKGROUND

• Reychler G, Boucard E, Peran L, Pichon R, Le Ber-Moy C, Ouksel H, Liistro G, Chambellan A, Beaumont M. One minute sit-to-stand test is an alternative to 6MWT to measure functional exercise performance in COPD patients. Clin Respir J. 2018 Mar;12(3):1247-1256. doi: 10.1111/crj.12658. Epub 2017 Jun 15.

  PMID: 28621019 BACKGROUND

• Quanjer PH, Stanojevic S, Cole TJ, Baur X, Hall GL, Culver BH, Enright PL, Hankinson JL, Ip MS, Zheng J, Stocks J; ERS Global Lung Function Initiative. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J. 2012 Dec;40(6):1324-43. doi: 10.1183/09031936.00080312. Epub 2012 Jun 27.

  PMID: 22743675 BACKGROUND

• Miller MR, Quanjer PH, Swanney MP, Ruppel G, Enright PL. Interpreting lung function data using 80% predicted and fixed thresholds misclassifies more than 20% of patients. Chest. 2011 Jan;139(1):52-9. doi: 10.1378/chest.10-0189. Epub 2010 Jun 3.

  PMID: 20522571 BACKGROUND

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Thomas Riegler, MSc

  Berner Reha Zentrum, Heiligenschwendi

  PRINCIPAL INVESTIGATOR

• Thomas Radtke, PD, Dr phil

  University of Zurich

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 1, 2020
• First Posted: October 8, 2020
• Study Start: September 16, 2020
• Primary Completion: March 25, 2021
• Study Completion: March 30, 2021
• Last Updated: July 21, 2021

Record last verified: 2021-07

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)