Appetite Lexicon Training

NCT04576585 | Completed

• 1 other identifier: 2020-214
• Study Type: interventional
• Target: 29
• Locations: 1 country
• Sites: 1

Brief Summary

A fundamental limitation to the application of appetitive sensations is how they are measured. The most common approach relies on untrained individuals to self-report the sensations they experience under a given set of conditions. Investigators believe this is problematic because assumptions made about participant ratings are likely not valid. The proposed protocol will permit examination of whether training on appetite lexicon enhances the reliability of appetite ratings. Investigators also hypothesize that different preloads will induce different magnitudes of appetite sensations (hunger, fullness, desire to eat, and prospective consumption) depending on their energy density.

Conditions

Appetitive Behavior

Outcome Measures

Primary Outcomes (4)

• specificity of responses

  to measure if training in appetite descriptors leads to more specific responses in the appetite questionnaire.

  start of study, day 1

• specificity of responses

  to measure if training in appetite descriptors leads to more specific responses in the appetite questionnaire.

  study completion, 9 weeks

• test reliability

  measure if training in appetite descriptors will result in higher reliability in the appetite questionnaire.

  start of study, day 1

• test reliability

  measure if training in appetite descriptors will result in higher reliability in the appetite questionnaire.

  study completion, 9 weeks

Study Arms (2)

Appetite lexicon training group

EXPERIMENTAL

They will get appetite lexicon training in week three.

Behavioral: Lexicon training

taste Lexicon training

ACTIVE COMPARATOR

They will get taste lexicon training In week three.

Behavioral: Lexicon training

Interventions

Lexicon training BEHAVIORAL

Participants will receive training on the lexicon of appetite on up to 3 days during the training week. This will entail reading written definitions, watching an instructional video, eating exercises and completing training exams demonstrating they understand the distinctions between appetitive terms (hunger, desire to eat, fullness, and prospective consumption). The training will require about 30 minutes to complete. To ensure the success of training, participants must verbally describe the definitions of the outcome sensations to a member of the research team and complete a written quiz with at least 90 % correct responses. Failure to satisfactorily convey understanding of the concepts will result in an offer to repeat the training 2 more times or be rejected from the study.

Appetite lexicon training group; taste Lexicon training

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• BMI 18-25 kg/m2.
• Age 18-60 years.
• Body weight fluctuation of \<2.5kg in the past 3 months.
• Fasting blood glucose below 6.1mmol/1 via capillary finger-stick blood sample using a SureStep glucometer (Lifescan, Milpitas, CA).
• Regular eating pattern (i.e., reliable timing of eating events (±1 hour at least 5 days/wk - absolute pattern is less important than consistency.))

You may not qualify if:

• Having an acute disease.
• Planning to initiate or terminate the use of medication known to affect appetite.
• Diagnosed relevant chronic health conditions (e.g. diabetes, cardiovascular disease).
• Allergies to eggs, peanuts, gluten, dairy, and carrots.
• Age 61+ years

Sponsors & Collaborators

• Purdue University: lead

Study Sites (1)

Purdue Univeristy

West Lafayette, Indiana, 47907, United States

Location

MeSH Terms

Conditions

Appetitive Behavior

Condition Hierarchy (Ancestors)

Behavior, Animal; Behavior

Study Officials

• Richard D Mattes, PhD

  Purdue University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: randomly assigned
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Distinguished Professor

Model Details: Investigators will randomly assign recruited participants to one of two groups. One group will receive training in the lexicon of appetite (Hunger, Fullness, Desire to Eat, and Prospective Consumption), and the other group will be trained in the basic tastes (Sweetness, Sourness, Bitterness, and Saltiness) as an attention control. All participants will participate in two preload trials with mixed meals before training and six paired preload trials after training. Trials will be held once per week. On another day of the trial week, participants will record their appetite during the waking hours of one day through an online survey. The total duration of participation will be in 9 weeks.

Study Record Dates

• First Submitted: September 10, 2020
• First Posted: October 6, 2020
• Study Start: August 25, 2020
• Primary Completion: August 30, 2022
• Study Completion: December 30, 2022
• Last Updated: May 7, 2024

Record last verified: 2024-05

Locations

US (1)