NCT04571411

Brief Summary

The aim of this study is to investigate the relationship between severity of envenomation and hematological parameter by detectig initial mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in pediatric patients presenting with a scorpion sting.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2020

Typical duration for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 25, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 1, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

December 1, 2020

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2023

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2023

Completed
Last Updated

October 14, 2020

Status Verified

October 1, 2020

Enrollment Period

2.2 years

First QC Date

September 25, 2020

Last Update Submit

October 12, 2020

Conditions

Scorpion Stings

Outcome Measures

Primary Outcomes (1)

  • The aim of this study is to investigate the relationship between severity of envenomation and hematological parameter

    All patient will be conducted to: 1. full history including: (Age, gender, weight, time and date of presentation 2. Full examination including : local General Cardiac examination Chest examination

    baseline

Interventions

CBCOTHER

The aim of this study is to investigate the relationship between severity of envenomation and hematological parameter by detectig initial mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in pediatric patients presenting with a scorpion sting.

Eligibility Criteria

Age0 Months - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

study on children stung by scorpion

You may qualify if:

  • a) Patients presented with scorpion sting

You may not qualify if:

  • All other envenomation or intoxications

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (8)

  • Adiguzel S, Ozkan O, Inceoglu B. Epidemiological and clinical characteristics of scorpionism in children in Sanliurfa, Turkey. Toxicon. 2007 May;49(6):875-80. doi: 10.1016/j.toxicon.2006.12.012. Epub 2007 Jan 10.

    PMID: 17286998RESULT

  • Shamoon Z, Peterfy RJ, Hammoud S, Khazaeni B. Scorpion Toxicity. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK430928/

    PMID: 28613678RESULT

  • Chippaux JP. Estimating the global burden of snakebite can help to improve management. PLoS Med. 2008 Nov 4;5(11):e221. doi: 10.1371/journal.pmed.0050221.

    PMID: 18986211RESULT

  • Ahmed AE, Abdel-Baseer KA, Saad K, Hassan AF, El-Houfey AA. Endocrinological and biochemical changes of scorpionism in children in Upper Egypt. Ther Adv Endocrinol Metab. 2015 Oct;6(5):210-6. doi: 10.1177/2042018815593034.

    PMID: 26445643RESULT

  • Ait Laaradia M, El Hidan MA, Marhoume F, Bouimeja B, Oufquir S, Sokar Z, Boumezzough A, Chait A. Buthus lienhardi venom and pathophysiological effects at the histological, hematological, biochemical and motor skills levels. Toxicon. 2018 May;146:106-113. doi: 10.1016/j.toxicon.2018.03.001. Epub 2018 Mar 9.

    PMID: 29526539RESULT

  • Horoz OO, Yildizdas D, Aslan N, Gokay SS, Ekinci F, Erdem S, Haytoglu Z, Sertdemir Y, Yilmaz HL. Is there any relationship between initial hematological parameters and severity of scorpion envenomation? Turk J Pediatr. 2020;62(3):394-404. doi: 10.24953/turkjped.2020.03.006.

    PMID: 32558413RESULT

  • Cupo P. Clinical update on scorpion envenoming. Rev Soc Bras Med Trop. 2015 Nov-Dec;48(6):642-9. doi: 10.1590/0037-8682-0237-2015.

    PMID: 26676487RESULT

  • Chippaux JP. Management of scorpion stings in Africa and the Mediterranean region. Med Sante Trop. 2016 May 1;26(2):130-3. doi: 10.1684/mst.2016.0571.

    PMID: 27412972RESULT

MeSH Terms

Conditions

Scorpion Stings

Condition Hierarchy (Ancestors)

Bites and StingsPoisoningChemically-Induced DisordersWounds and Injuries

Study Officials

  • Yasser Gamal Abl Elrahman, lecture

    Assiut University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sarah Osama Mohamed, master

CONTACT

01026662002saso_monier_2020@yahoo.com

Azza Ahmed Eltayeb, professor

CONTACT

01006863277

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident Doctor

Study Record Dates

First Submitted

September 25, 2020

First Posted

October 1, 2020

Study Start

December 1, 2020

Primary Completion

March 1, 2023

Study Completion

September 1, 2023

Last Updated

October 14, 2020

Record last verified: 2020-10