Platelet and Red Blood Cell Volume Indices as Inflammatory Biomarkers in Ankylosing Spondylitis
1 other identifier
observational
70
1 country
1
Brief Summary
this study aims to determine the relatioships among the NLR ,PLR ,MLR ,red cell volume and platelet volume indices levels as biomarkers in ankylosing spondylitis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Aug 2023
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2023
CompletedFirst Submitted
Initial submission to the registry
August 10, 2023
CompletedFirst Posted
Study publicly available on registry
August 18, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2024
CompletedAugust 18, 2023
August 1, 2023
6 months
August 10, 2023
August 10, 2023
Conditions
Outcome Measures
Primary Outcomes (2)
platelet
platelet cell volume indices
6 months
Red blood cell
red blood cell volume indices
6 months
Study Arms (2)
cases group
control group
Interventions
Eligibility Criteria
PATIENT WITH DISEASE DURATION OF MORE THAN 6 MONTHS -AGE MORE THAN 18 YEARS
You may qualify if:
- PATIENT WITH DISEASE DURATION OF MORE THAN 6 MONTHS
- AGE MORE THAN 18 YEARS
You may not qualify if:
- PATIENT WITH CARDIAC ,CEREBROVASCULAR AND HEMATOLOGIC DIEASE
- PTIENT WITH HYPERTENSION ,DIABETES ,METABOLIS SYNDROMES AND OTHER AUTOIMMUNE RHEUMATIC DISEASES.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sohag Universitylead
Study Sites (1)
Sohag university Hospital
Sohag, Egypt
Related Publications (4)
Azab B, Torbey E, Singh J, Akerman M, Khoueiry G, McGinn JT, Widmann WD, Lafferty J. Mean platelet volume/platelet count ratio as a predictor of long-term mortality after non-ST-elevation myocardial infarction. Platelets. 2011;22(8):557-66. doi: 10.3109/09537104.2011.584086. Epub 2011 Jun 30.
PMID: 21714700BACKGROUNDCoutant F, Miossec P. Evolving concepts of the pathogenesis of rheumatoid arthritis with focus on the early and late stages. Curr Opin Rheumatol. 2020 Jan;32(1):57-63. doi: 10.1097/BOR.0000000000000664.
PMID: 31644463BACKGROUNDBekdas M, Goksugur SB, Sarac EG, Erkocoglu M, Demircioglu F. Neutrophil/lymphocyte and C-reactive protein/mean platelet volume ratios in differentiating between viral and bacterial pneumonias and diagnosing early complications in children. Saudi Med J. 2014 May;35(5):442-7.
PMID: 24825803BACKGROUNDKumano Y, Hasegawa Y, Kawahara T, Yasui M, Miyoshi Y, Matsubara N, Uemura H. Pretreatment Neutrophil to Lymphocyte Ratio (NLR) Predicts Prognosis for Castration Resistant Prostate Cancer Patients Underwent Enzalutamide. Biomed Res Int. 2019 Jan 20;2019:9450838. doi: 10.1155/2019/9450838. eCollection 2019.
PMID: 30800682BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
MOHAMMED A ESMAIL, assistant professor
CONTACT
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident-rheumatology department-sohag general hospital
Study Record Dates
First Submitted
August 10, 2023
First Posted
August 18, 2023
Study Start
August 1, 2023
Primary Completion
February 1, 2024
Study Completion
February 1, 2024
Last Updated
August 18, 2023
Record last verified: 2023-08