Dynamics of the Capillary Lactate Levels in OHCA
1 other identifier
observational
100
1 country
1
Brief Summary
Serial capillary lactate measurements during cardiopulmonary resuscitation (CPR) in patients with out-of-hospital cardiac arrest (OHCA).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Apr 2019
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2019
CompletedFirst Submitted
Initial submission to the registry
September 24, 2020
CompletedFirst Posted
Study publicly available on registry
October 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
May 31, 2022
CompletedNovember 24, 2023
November 1, 2023
2.8 years
September 24, 2020
November 22, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
ROSC
In patients with ROSC the capillary lactate level will be lower compare to the non ROSC group.
2 years
Comparison between primary and secondary cardiac arrest
Initial and serial values of capillary lactate will be lower in patients with primary out-of- hospital cardiac arrest (OHCA)
2 years
No ROSC
Serial values of capillary lactate will be higher in patients without ROSC
2 years
Interventions
In this study capillary lactate will be measured every 10 minute during CPR.
Eligibility Criteria
For this study will be eligible all patients with OHCA due to primary or secondary cardiac arrest.
You may qualify if:
- adults with OHCA
You may not qualify if:
- children with OHCA
- trauma
- hypothermia
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Community health center Maribor, Prehospital unit
Maribor, 2000, Slovenia
Related Publications (4)
Lurie KG, Nemergut EC, Yannopoulos D, Sweeney M. The Physiology of Cardiopulmonary Resuscitation. Anesth Analg. 2016 Mar;122(3):767-783. doi: 10.1213/ANE.0000000000000926.
PMID: 26562060BACKGROUNDPatil KD, Halperin HR, Becker LB. Cardiac arrest: resuscitation and reperfusion. Circ Res. 2015 Jun 5;116(12):2041-9. doi: 10.1161/CIRCRESAHA.116.304495.
PMID: 26044255BACKGROUNDCorral Torres E, Hernandez-Tejedor A, Suarez Bustamante R, de Elias Hernandez R, Casado Florez I, San Juan Linares A. Prognostic value of venous blood analysis at the start of CPR in non-traumatic out-of-hospital cardiac arrest: association with ROSC and the neurological outcome. Crit Care. 2020 Feb 22;24(1):60. doi: 10.1186/s13054-020-2762-5.
PMID: 32087761BACKGROUNDSariaydin T, Corbacioglu SK, Cevik Y, Emektar E. Effect of initial lactate level on short-term survival in patients with out-of-hospital cardiac arrest. Turk J Emerg Med. 2017 May 15;17(4):123-127. doi: 10.1016/j.tjem.2017.05.003. eCollection 2017 Dec.
PMID: 29464213BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Matej Strnad, MD, PhD
University medical center Maribor
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assoc. Professor
Study Record Dates
First Submitted
September 24, 2020
First Posted
October 1, 2020
Study Start
April 1, 2019
Primary Completion
December 31, 2021
Study Completion
May 31, 2022
Last Updated
November 24, 2023
Record last verified: 2023-11
Data Sharing
- IPD Sharing
- Will not share