NCT04563611

Brief Summary

Hamstring muscle injuries (HMI) occurs frequently during excessive motions of the physiologic capability of these muscles. It is reported in the literature that impairments in muscle architecture, such as a decrease in the eccentric strength of the hamstring muscles of the knee (lengthening and contraction of the muscle), delay in the reaction time of the hamstring muscles, overactivity of the hamstring muscles, a decrease in the length of the hamstring muscle fibers, and inadequate cognitive functions may lead to HMI. Preventive and therapeutic exercises of HMI consist many different eccentric exercises, such as the Askling L-protocol and particularly Nordic hamstring exercise, for increasing the hamstring flexibility. However, it has been stated in recent studies that hamstring muscles should not be focused on alone, and a holistic exercise intervention that includes and addresses the present risk factors related to HMI is needed. Within our knowledge, the effect of a defined or improved holistic exercise approach to prevent and/or treat HMI has not been studied in the literature. Considering the risk factors underlying HMI, an exercise involving a holistic approach is needed to prevent all the risk factors. Turkish Get Up (TGU) exercise is a kind of cognitive exercise which activates all muscles and let to contract simultaneously during standing up from the supine position and turning back in 7 stages. Since the exercise originates from former Turkish athletes, it has been included in the literature as TGU. Hence, the exercise originates from former Turkish athletes, it has called as TGU. TGU exercise improves the effective and strong transition ability of the body while developing the pattern of standing up from the lying position on the floor and turning back by increasing condition/ endurance. Meanwhile, this exercise is a progressive coordinative and cognitive exercise, it requires completing each step before the next movement. The role of cognitive skills and neuroscience in the interpretation, prediction and improvement of sports performance is getting popular in recent years. Previous researches reported that athletes with reduced cognitive skills had lower sportive achievements. It has also stated that the impairment in cognitive skills tend muscles to be injured. However, no studies that investigate the effectiveness of cognitive function in preventing HMI have been encountered. So, the present study will be the first study investigating effects of a special exercise addressing cognitive function which is generally ignored in the treatment of HMI. It is aimed to figure out whether Turkish Get Up exercise or Supine sliding leg curls and Nordic Hamstring exercises are more effective on hamstring muscle function, ınjury risk, agility and cognitive function. Healthy recreational people aged between 18-25 will assign to this study. The participants will randomly be allocated four groups (Nordic protocol group, Supine sliding leg curls group, Turkish Get Up (TGU) and control group). The exercise protocols will be applied two days a week for 6 weeks, and the control group will receive no special exercise training. Participants' hamstring muscle strengths will be evaluated with ISOMED 2000 isokinetic dynamometer, the hamstring flexibility with digital inclinometer device, injury risk with FMS™, agility with T-agility test, and the cognitive function with CNS Vital Signs in computer environment at baseline and 6 weeks after interventions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 21, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 24, 2020

Completed
5 months until next milestone

Study Start

First participant enrolled

February 9, 2021

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 21, 2021

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 14, 2022

Completed
Last Updated

February 15, 2022

Status Verified

February 1, 2022

Enrollment Period

2 months

First QC Date

September 21, 2020

Last Update Submit

February 14, 2022

Conditions

Outcome Measures

Primary Outcomes (5)

  • Hamstring Muscle Strength

    Participants hamstring muscle strengths will be evaluated with ISOMED 2000 isokinetic dynamometer

    6 weeks

  • Hamstring Flexibility

    In this study, Individuals' evaluations of hamstring flexibility will be assessed by the active knee extension test (ICC: 0.96) with maximum hip flexion.

    6 weeks

  • Cognitive Function

    The lower (reaction time and visual-perceptual ability) and upper level (working memory, inhibitory control, and cognitive flexibility) cognitive functions of the individuals participating in the study will be evaluated with the computer assisted CNSVS test battery

    6 weeks

  • Injury risk

    Injury risk analysis of individuals will be made using the strength differences between the two sides, H: Q ratios (conventional and functional ratio) and functional movement screen (FMS), which will be obtained from the isokinetic measurement results.

    6 weeks

  • Agility

    Agility performances of individuals will be evaluated with the Agility T test.

    6 weeks

Study Arms (8)

Muscle strength

NO INTERVENTION

Participants hamstring muscle strengths will be evaluated with ISOMED 2000 isokinetic dynamometer

Hamstring Flexibility

NO INTERVENTION

In this study, Individuals' evaluations of hamstring flexibility will be assessed by the active knee extension test (ICC: 0.96) with maximum hip flexion.

Cognitive Function

NO INTERVENTION

The lower (reaction time and visual-perceptual ability) and upper level (working memory, inhibitory control, and cognitive flexibility) cognitive functions of the individuals participating in the study will be evaluated with the computer assisted CNSVS test battery

Injury risk

NO INTERVENTION

Injury risk analysis of individuals will be made using the strength differences between the two sides, H: Q ratios (conventional and functional ratio) and functional movement screen (FMS), which will be obtained from the isokinetic measurement results.

Nordic hamstring exercise

EXPERIMENTAL

To perform this exercise, participants will be asked to stand in an upright position on their knees. The hands and arms will be positioned on the chest and held by the physical therapist at the heels of the individuals. The individual will then be asked to lower the upper body forward as slowly as possible. Verbal commands will be given throughout the movement so that the hip and trunk smoothness is not disturbed

Other: Nordic hamstring exerciseOther: Control Group

Supine Sliding Leg Curls

EXPERIMENTAL

The persons will be started to exercise in the hook position, with hands-on their back, with their knees next to the body, in a flexion position of approximately 60 °. Participants will be asked to first build a bridge, then maintain this position and slowly slide the slippery apparatus under their feet to bring their knees to full extension.

Other: Askling L-ProtocolOther: Control Group

Turkish Get-up exercise

EXPERIMENTAL

TG exercise, in 7 different steps (1. Starting position, 2. Supine girya lifting, 3. Elbow supported kettlebell lifting, 4. Hand supported kettlebell lifting, 5. High bridge, 6. Half above knee and lunge position, 7. Standing up) and the return of these different steps.

Other: Turkish Get-up exerciseOther: Control Group

Agility

NO INTERVENTION

Agility performances of individuals will be evaluated with the Agility T-test.

Interventions

TG exercise, in 7 different steps (1. Starting position, 2. Supine girya lifting, 3. Elbow supported kettlebell lifting, 4. Hand supported kettlebell lifting, 5. High bridge, 6. Half above knee and lunge position, 7. Standing up) and the return of these different steps.

Turkish Get-up exercise

he protocol consists of 3 different exercises. These are exercise 1 aimed at increasing flexibility, exercise 2 providing strength and trunk / pelvis stabilization, and exercise 3 aiming at specific strengthening. Pain is not allowed to be provoked when performing the exercises.

Supine Sliding Leg Curls

To perform this exercise, participants will be asked to stand in an upright position on their knees. Hands and arms will be positioned on the chest and the individuals will be held by the physiotherapist at their heels. The individual will then be asked to lower the upper body forward as slowly as possible. Verbal commands will be given throughout the movement so that the hip and trunk smoothness is not disturbed.

Nordic hamstring exercise

No exercise will be applied to the individuals in the control group. At the end of the 6-week period, all parameters will be evaluated again.

Nordic hamstring exerciseSupine Sliding Leg CurlsTurkish Get-up exercise

Eligibility Criteria

Age18 Years - 25 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Being between the ages of 18-25
  • Body mass index (BMI) being between 18.5-24.9 kg / m 2
  • Volunteering to participate in the study
  • Having the skills to do the tests and exercises to be applied
  • Being a healthy recreationally active male individual (Individuals with sufficient physical activity level according to the International Physical Activity Questionnaire (IPAQ) Short form (\> 3000 metabolic equivalent (MET) -min / week) will be included)

You may not qualify if:

  • Having a history of lower extremity injury and / or hamstring strain within the past year
  • Having a sensory problem that prevents participation in the study
  • Have any musculoskeletal, neurological, respiratory, or cardiovascular risk factors that limit exercise
  • Using drugs or nutritional supplements that can be considered doping according to the World Anti-Doping Agency (WADA)
  • Having a history of malignant disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ankara Yıldırım Beyazıt University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Ankara, Etlik, 06010, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Control Groups

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Healthy recreational people aged between 18-25 will assign to this study. The participants will randomly be allocated four groups (Nordic protocol group, Supine sliding leg curls group, Turkish Get Up (TGU) and control group).
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Çağlar Soylu

Study Record Dates

First Submitted

September 21, 2020

First Posted

September 24, 2020

Study Start

February 9, 2021

Primary Completion

April 21, 2021

Study Completion

February 14, 2022

Last Updated

February 15, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share

Locations