Effect of Pilates Training in Patients With Multiple Sclerosis

NCT04548206 | Completed

• 1 other identifier: 166
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

Knee flexor and extensor muscle weakness in MS patients causes a decrease in walking distance and is an important determinant of walking capacity. Exercise training has beneficial effects on muscle strength, balance, and walking in MS patients. Although the effects of aerobic and resistant exercise training in MS patients are often emphasized, today the effect of different exercise types is also wondered. Pilates is a core stability-based exercise method that improves endurance, flexibility, movement, posture, and respiratory control. The aim of this study is to examine the effect of Pilates training on sensation, muscle strength, balance, and walking in MS patients.

Conditions

Multiple Sclerosis

Keywords

Multiple Sclerosis; sensation; gait; Pilates

Outcome Measures

Primary Outcomes (9)

• Gait

  Gait parameters will be assessed via the G-Walk on two separate occasions. The G-Walk is a device that is worn on the waist via an elastic belt. The G-Walk is built with a triaxial accelerometer 16 bit/axes with multiple sensitivity, a triaxial magnetometer 13 bit and a triaxial gyroscope 16 bit/axes with multiple sensitivity. This hardware is capable of acquiring and transmitting data to a computer through a Bluetooth connection and at the end of each analysis an automatic report containing the gait assessment results is ready to be analyzed. Gait symmetry values of the right and left sides are obtained within this report. While the symmetry index ranges from 0 to 100, a value closer to 100 indicates that the gait is more symmetrica.

  5 minutes

• Balance

  The Modified Sensory Organization Test, which is performed using computerized posturography, measures postural sway in response to 4 different sensory conditions is measured using a force platform.

  10 minutes

• Light touch-pressure sensation

  Light touch-pressure sensation will be assessed using a full Semmes-Weinstein Monofilament (SWM) test kit (North Coast Medical, San Jose, CA, USA).

  10 minutes

• Vibration sensation

  Duration of vibration sensation will be measured using 128-Hz frequency tuning fork (Elcon1 Medical Instruments, Tuttlingen, Germany).

  10 minutes

• Two-point discrimination

  Two-point discrimination sensation of the foot sole will be evaluated using an aesthesiometer (Baseline1, White Plains, New York, USA).

  10 minutes

• Position sensation of knee joint

  Open kinetic chain position of both knees will be evaluated using a Dualer IQ Digital Inclinometer (J-Tech Medical, Midvale, UT, USA).

  5 minutes

• Knee proprioception

  Knee proprioception will be evaluated with the active joint reposition test using the isokinetic system (Cybex Norm, Humac, CA, USA).

  10 minutes

• Position sensation of trunk

  Position sensation of trunk will be evaluated using a Dualer IQ Digital Inclinometer (J-Tech Medical, Midvale, UT, USA).

  10 minutes

• Knee strength

  Knee strength will be evaluated using the isokinetic system (Cybex Norm, Humac, CA, USA).

  20 minutes

Study Arms (2)

Pilates training

EXPERIMENTAL

60 minutes of Pilates training will be performed for 8 weeks.

Other: Pilates training

Control group

PLACEBO COMPARATOR

The control group will be taught relaxation exercises and will be asked to perform the exercises at home.

Other: control

Interventions

Pilates training OTHER

The program consisted of core-based Pilates exercises on the mat for 60 minutes.

Pilates training

control OTHER

The program consisted of progressive relaxation exercises at home.

Control group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years of age
• Having a diagnosis of "Multiple Sclerosis"
• Relapse free in the last 3 mounts
• Having an ambulatory status (Expanded Disability Status Scale score ≤ 6 )
• No diagnosis of depression

You may not qualify if:

• Any cardiovascular, orthopedic, visual, hearing and perception problems that may affect the results of the research.

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Gazi University

Ankara, Turkey (Türkiye)

Location

Related Publications (2)

• Citaker S, Gunduz AG, Guclu MB, Nazliel B, Irkec C, Kaya D. Relationship between foot sensation and standing balance in patients with multiple sclerosis. Gait Posture. 2011 Jun;34(2):275-8. doi: 10.1016/j.gaitpost.2011.05.015. Epub 2011 Jun 16.

  PMID: 21683600 BACKGROUND

• Bulguroglu I, Guclu-Gunduz A, Yazici G, Ozkul C, Irkec C, Nazliel B, Batur-Caglayan HZ. The effects of Mat Pilates and Reformer Pilates in patients with Multiple Sclerosis: A randomized controlled study. NeuroRehabilitation. 2017;41(2):413-422. doi: 10.3233/NRE-162121.

  PMID: 28946576 BACKGROUND

MeSH Terms

Conditions

Multiple Sclerosis

Interventions

Exercise Movement Techniques

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Intervention Hierarchy (Ancestors)

Physical Therapy Modalities; Therapeutics

Study Officials

• Cagla Ozkul, Phd

  Gazi University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Model Details: prospective randomize controlled study

Study Record Dates

• First Submitted: September 7, 2020
• First Posted: September 14, 2020
• Study Start: September 14, 2020
• Primary Completion: July 29, 2022
• Study Completion: July 29, 2022
• Last Updated: August 5, 2022

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)