The Effects of Pilates-Based Core Stabilization Training in Multiple Sclerosis

NCT04252053 | Completed

• 1 other identifier: 59491012-604.01.02-
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Multiple Sclerosis (MS) is a chronic, autoimmune and neurodegenerative disease characterized by inflammation and progressive demyelination of the central nervous system. It is characterized by muscle weakness, balance and coordination disorder, which is more common in the lower extremities and trunk muscles. Over time, these symptoms decrease the individual's level of physical activity, mobility and quality of life, leading to further deterioration of the disorder. One of the most important problems that cause these problems in individuals with MS is reduced core stabilization. Decrease in core stabilization affects the quality of limb movements as well as trunk stability when considering the kinetic chain in the body. Pilates-based core stabilization training (PBCST) are a controlled exercise form used to improve the stabilization of trunk muscles. There are no studies on the effect of this training on lower extremity isokinetic muscle strength in individuals with MS. The aim of this study is to determine the effect of PBCST on lower extremity muscle strength, postural sway and kinetic chain in individuals with MS.

Conditions

Multiple Sclerosis

Keywords

Multiple sclerosis; Pilates; Core stability; Isokinetic strength; Postural sway

Outcome Measures

Primary Outcomes (2)

• Isokinetic strength

  Concentric isokinetic muscle strength of the knee flexor and extensor muscles will be evaluated at angular velocities of 30,60 and 90°/s.

  8 weeks

• Postural sways

  Postural sways will be evaluated with biodex balance system in different condition such as open eyes on firm and foam surface, closed eyes on firm and foam surface, tandem stance on firm and foam surface,

  8 weeks

Secondary Outcomes (7)

• Core strength

  8 weeks

• Core endurance

  8 weeks

• Balance

  8 weeks

• Mobility

  8 weeks

• Fatigue

  8 weeks

Study Arms (2)

Supervised Pilates-Based Core Stability Training Group

EXPERIMENTAL

In order to detect the effects of pilates-based core stabilization training (PBCST) on isokinetic knee strength and postural sways, individuals with MS will receive pilates-based core stabilization training for 8 weeks and 2 days a week. One educational session will perform to teach basic principles of pilates based training. Individuals in this group will receive treatment at the clinic by physiotherapist supervision. All sessions will be individualized (not group training).

Other: Pilates Based Core Stabilization Training

Home exercise group

ACTIVE COMPARATOR

The home exercise group will perform the same PBCST exercises at home during the same period (8 weeks, 2 days a week) as the brochures prepared for them. Individuals in this group will receive one educational session which includes basic principles of pilates and one session which includes two-week exercise program. Participants will be invited to the clinic every two weeks to ensure the progression of the exercises and the exercise program will be updated.

Other: Home based exercise

Interventions

Pilates Based Core Stabilization Training OTHER

Pilates-based core stabilization training (PBCST) is a controlled form of exercise provided improvement in stabilization of abdominal and back muscles.

Supervised Pilates-Based Core Stability Training Group

Home based exercise OTHER

Home exercises which include pilates based core stabilization training will be structured for the people with MS according to their physical condition and will perform at home by them.

Home exercise group

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being diagnosed with MS according to McDonald's criteria
• Disability level less than 6 according to EDSS (Expanded Disability Status Scale) score
• No attacks during the last 3 months
• Being an ambulatory
• Volunteering to participate in the study

You may not qualify if:

• Having orthopedic, neurological, psychological, etc. diseases that accompany MS and may affect treatment outcomes
• Doing regular sports
• Being involved in another physiotherapy and rehabilitation program related to MS

Sponsors & Collaborators

• Istanbul University - Cerrahpasa: lead

Study Sites (1)

Istanbul University-Cerrahpasa

Istanbul, 34147, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist, Research Assistant

Study Record Dates

• First Submitted: January 27, 2020
• First Posted: February 5, 2020
• Study Start: February 6, 2020
• Primary Completion: January 3, 2021
• Study Completion: January 3, 2021
• Last Updated: January 7, 2021

Record last verified: 2021-01

Locations

TU (1)