NCT04541498|Completed
Impact of Air Pollution and Climate Changes on the Epidemiology of Cardiovascular Disease
PL-PARTICLES
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PL-PARTICLES
Sponsor study identifier
observational
150,000
1 country
1
Study Start
January 1, 2019
Actual (reported)Primary Completion
August 1, 2021
Actual (reported)Study Completion
January 1, 2022
Actual (reported)Despite the fact that the topic of air pollution has been in focus of researchers for many years, there are no big studies that take up the matter of its influence on acute coronary, cerebral syndromes and CVD mortality in Europe. Taking into consideration the scarce number of surveys from Europe the investigators decided to analyze the impact of air pollution on cardiovascular diseases and CVD mortality in Poland.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 1, 2022
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2019
Actual (reported)August 21, 2020
Actual (reported)September 9, 2020
Actual (reported)August 1, 2021
Actual (reported)January 1, 2022
Actual (reported)Incidence of acute coronary syndromes
Number of acute coronary syndromes related with impact of air pollution
Through study completion, an average of 1 year
Incidence of cardiovascular mortality
Number of cardiovascular deaths related with impact of air pollution
Through study completion, an average of 1 year
Incidence of acute cerebral syndromes
Number of acute cerebral syndromes related with impact of air pollution
Through study completion, an average of 1 year
Exposure to short term long term effects of air pollution and climate change
Exposure to short term long term effects of air pollution and climate change
To assess the short- and long- term impact of air pollution and climate changes
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
In primary we focus on Podlaskie Voivodeship. The region is located in north-east Poland which is a developing country as well as one of the poorest regions of the EU. Within four national parks, the region is widely known as the Green Lungs of Poland, mainly due to large areas covered by forests, lack of factories, and relatively low industrialization.
Department of Invasive Cardiology Medical University of Białystok 24A M. Skłodowskiej-Curie St.
Bialystok, 15-276, Poland
Kuzma L, Pogorzelski S, Struniawski K, Dobrzycki S, Bachorzewska-Gajewska H. Effect of air pollution on the number of hospital admissions for acute coronary syndrome in elderly patients. Pol Arch Intern Med. 2020 Jan 31;130(1):38-46. doi: 10.20452/pamw.15064. Epub 2019 Nov 19.
Kuzma L, Pogorzelski S, Struniawski K, Bachorzewska-Gajewska H, Dobrzycki S. Exposure to air pollution-a trigger for myocardial infarction? A nine-year study in Bialystok-the capital of the Green Lungs of Poland (BIA-ACS registry). Int J Hyg Environ Health. 2020 Aug;229:113578. doi: 10.1016/j.ijheh.2020.113578. Epub 2020 Aug 3.
Lukasz Kuzma, MD, PhD
Medical University of Bialystok, Department of Invasive Cardiology
150,000 participants (actual enrollment reported by the registry).
First Submitted
August 21, 2020
First Posted
September 9, 2020
Study Start
January 1, 2019
Actual (reported)Intervention of Air Pollution and Acute Coronary Syndrome
Contact the study team to confirm eligibility.
Kuzma L, Struniawski K, Pogorzelski S, Bachorzewska-Gajewska H, Dobrzycki S. Gender Differences in Association between Air Pollution and Daily Mortality in the Capital of the Green Lungs of Poland-Population-Based Study with 2,953,000 Person-Years of Follow-Up. J Clin Med. 2020 Jul 23;9(8):2351. doi: 10.3390/jcm9082351.
Kuzma L, Wanha W, Kralisz P, Kazmierski M, Bachorzewska-Gajewska H, Wojakowski W, Dobrzycki S. Impact of short-term air pollution exposure on acute coronary syndrome in two cohorts of industrial and non-industrial areas: A time series regression with 6,000,000 person-years of follow-up (ACS - Air Pollution Study). Environ Res. 2021 Jun;197:111154. doi: 10.1016/j.envres.2021.111154. Epub 2021 Apr 17.
Rogalska E, Kurasz A, Kuzma L, Bachorzewska-Gajewska H, Dobrzycki S, Kozinski M, Sobkowicz B, Tomaszuk-Kazberuk A. Comparing Atrial-Fibrillation Validated Rapid Scoring Systems in the Long-Term Mortality Prediction in Patients Referred for Elective Coronary Angiography: A Subanalysis of the Bialystok Coronary Project. Int J Environ Res Public Health. 2022 Aug 21;19(16):10419. doi: 10.3390/ijerph191610419.
Primary Completion
August 1, 2021
Actual (reported)Study Completion
January 1, 2022
Actual (reported)Last Updated
January 10, 2022
Record last verified: 2021-09
All IPD that underlie results in a publication
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Source: ClinicalTrials.gov.
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