NCT04374110

Brief Summary

Hospitalized patients with COVID-19 will be included in the study in centers around Poland. After the hospitalization, a short questionnaire will be completed, including pre-hospitalization diagnoses, pre-hospitalization medications, clinical status on admission, the course, complication and the duration of hospitalization. The questionnaire will be available in paper form and on-line.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 22, 2020

Completed
13 days until next milestone

First Posted

Study publicly available on registry

May 5, 2020

Completed
Same day until next milestone

Study Start

First participant enrolled

May 5, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 24, 2020

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 24, 2021

Completed
Last Updated

May 6, 2020

Status Verified

May 1, 2020

Enrollment Period

2 months

First QC Date

April 22, 2020

Last Update Submit

May 5, 2020

Conditions

Keywords

Angiotensin converting enzyme inhibitorsAngiotensin 2 receptor blockersRenin angiotensin systemCOVID-19Hypertension

Outcome Measures

Primary Outcomes (1)

  • Adverse events

    Death, myocardial infarction, heart failure, myocarditis, acute renal failure, stroke

    through study completion, an average of 2 weeks

Secondary Outcomes (3)

  • Number of participants with death, myocardial infarction, heart failure, myocarditis, acute renal failure, stroke

    through study completion, an average of 2 weeks

  • Ventilation during hospitalization

    through study completion, an average of 2 weeks

  • Number of participants with death, myocardial infarction, heart failure, myocarditis, acute renal failure, stroke

    prolonged follow up, through study completion, an average of one year

Study Arms (3)

Hospitalized patients with COVID-19

Hospitalized patients with COVID-19 will be included in the study in centers around Poland.

Other: Clinical data

Infected SARS-CoV-2 patients

patients with SARS-CoV-2 infection not requiring hospitalization

Other: Clinical data

Controls

structure-matched and co-existing disease matched control group from the general population.

Other: Clinical data

Interventions

Clinical characteristics from medical records

ControlsHospitalized patients with COVID-19Infected SARS-CoV-2 patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Hospitalized patients with COVID-19 will be included in the study in centers around Poland.

You may qualify if:

  • Hospitalized patients with COVID-19

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Institute of Cardiology

Warsaw, Poland

RECRUITING

MeSH Terms

Conditions

HypertensionCardiovascular DiseasesCOVID-19

Condition Hierarchy (Ancestors)

Vascular DiseasesPneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Andrzej Januszewicz, MD, PhD

    National Institute of Cardiology

    PRINCIPAL INVESTIGATOR
  • Tomasz Hryniewiecki, MD, PhD

    National Institute of Cardiology

    PRINCIPAL INVESTIGATOR
  • Rafal Dabrowski, MD, PhD

    National Institute of Cardiology

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Aleksander Prejbisz, MD, PhD

CONTACT

Piotr Dobrowolski, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 22, 2020

First Posted

May 5, 2020

Study Start

May 5, 2020

Primary Completion

June 24, 2020

Study Completion

August 24, 2021

Last Updated

May 6, 2020

Record last verified: 2020-05

Locations