A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test

NCT04529122 | Recruiting

• 1 other identifier: MX39897
• Study Type: observational
• Target: 15,000
• Locations: 30 countries
• Sites: 133

Brief Summary

WAYFIND-R is a registry that aims to capture high-quality real-world data linking next-generation sequencing, treatments and outcomes from cancer patients diagnosed with a solid tumour. The WAYFIND-R has three main overarching objectives: 1. To provide a platform to support the design and conduct of clinical and epidemiological research; 2. To develop an evidence-generation platform to better understand health outcomes and cancer care processes; and 3. To characterize the treatments and clinical course of solid tumor cancers in patients who have undergone NGS testing.

Conditions

Solid Tumours

Outcome Measures

Primary Outcomes (1)

• Overall Survival

  From date of registry entry until death, for up to 5 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Male and Female adult participants who are diagnosed with solid tumour cancers (at any anatomical location) and at any stage of the disease who have undergone an NGS test.

You may qualify if:

• Participant is an adult (according to the age of majority as defined by local regulations)
• Participant is currently diagnosed with any type of solid tumour cancer, at any stage of the disease, at the enrollment date (informed consent date)
• Participant has undergone NGS testing, no longer than 3 months prior to the enrollment date, irrespective of the availability of test results
• Informed consent has been obtained from the participant or legally authorized representative, as per local regulations

You may not qualify if:

• Participant has a prior or current diagnosis of haematological malignancy

Sponsors & Collaborators

• Hoffmann-La Roche: lead

Study Sites (138)

Instituto Alexander Fleming

Buenos Aires, 1426, Argentina

RECRUITING

CEMIC

Buenos Aires, C1431FWN, Argentina

RECRUITING

Lkh-Univ. Klinikum Graz

Graz, 8036, Austria

RECRUITING

Hospital Moinhos de Vento

Porto Alegre, Rio Grande do Sul, 90035-001, Brazil

RECRUITING

Instituto do Cancer do Estado de Sao Paulo - ICESP

São Paulo, São Paulo, 01246-000, Brazil

TERMINATED

Hospital Alemao Oswaldo Cruz

São Paulo, São Paulo, 01323-903, Brazil

RECRUITING

D'or Instituto de Pesquisa e Educação

Rio de Janeiro, Brazil

RECRUITING

Beneficencia Portuguesa de Sao Paulo

São Paulo, 01321-00, Brazil

RECRUITING

Alberta Health Services

Calgary, Alberta, T2N 4N2, Canada

RECRUITING

The Ottawa Hospital - General Campus

Ottawa, Ontario, K1H 8L6, Canada

RECRUITING

Medicina de Precisión - Celerity

Las Condes, 7560908, Chile

RECRUITING

Centro de Cancer Pontificie Universidad Catolica de Chile

Santiago, 8330074, Chile

COMPLETED

Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo

Bogota, D.C., 110131, Colombia

RECRUITING

Fundacion Cardioinfantil

Bogotá, Colombia

RECRUITING

Organizacion Sanitas Internacional

Bogotá, Colombia

RECRUITING

Fundacion Clinica Valle del Lili

Cali, Colombia

RECRUITING

Instituto Cancerología Medellin

Medellín, 050024, Colombia

RECRUITING

Clinica ASTORGA

Medellín, 50010, Colombia

RECRUITING

International Medical Center

Cairo, Egypt

RECRUITING

East Tallinn Central Hospital

Tallinn, 11312, Estonia

RECRUITING

North Estonia Medical Centre Foundation

Tallinn, 13419, Estonia

RECRUITING

Tartu Uni Hospital

Tartu, 51014, Estonia

RECRUITING

Chu Amiens - Picardie

Amiens, 80054, France

RECRUITING

Hopital Jean Minjoz

Besançon, 25030, France

RECRUITING

Centre Hospitalier de Béthune-Beuvry

Béthune, 62408, France

RECRUITING

Chu Brest - Hôpital Morvan

Brest, 29200, France

RECRUITING

Centre Francois Baclesse

Caen, 14076, France

RECRUITING

Centre Hospitalier de Chauny

Chauny, 02300, France

RECRUITING

Centre Jean Perrin

Clermont-Ferrand, 63011, France

RECRUITING

Groupe Hospitalier Public Du Sud De L'Oise GHPSO

Creil, 60109, France

RECRUITING

Centre hospitalier universitaire Dijon-Bourgogne

Dijon, 21079, France

COMPLETED

Hôpital Franco-Britannique- Fondation Cognacq-Jay

Levallois-Perret, 92300, France

RECRUITING

Centre Oscar Lambret

Lille, 59020, France

RECRUITING

Centre Leon Berard

Lyon, 69373, France

RECRUITING

APHM

Marseille, 13385, France

RECRUITING

Hopital de La Timone - CHU de Marseille

Marseille, 13385, France

RECRUITING

Institut Régional du Cancer de Montpellier

Montpellier, 34298, France

RECRUITING

Institut Curie

Paris, 75005, France

RECRUITING

CH de Cornouailles

Quimper, 29107, France

RECRUITING

Centre Eugene Marquis

Rennes, 35000, France

RECRUITING

CHU Saint Etienne - Hôpital Nord

Saint-Etienne, 42055, France

RECRUITING

Hôpital Privé de la Loire, Ramsay Saint Etienne

Saint-Etienne, 42100, France

RECRUITING

CHI de Toulon - Hôpital Sainte Musse

Toulon, 83056, France

RECRUITING

Gustave Roussy

Villejuif, 94800, France

RECRUITING

HELIOS Klinikum Bad Saarow

Bad Saarow, 15526, Germany

RECRUITING

DRK Kliniken Berlin

Berlin, 12559, Germany

RECRUITING

Universitätsklinikum Halle (Saale)

Halle, 06120, Germany

RECRUITING

Asklepios Klinik Altona

Hamburg, 22763, Germany

RECRUITING

Medizinische Hochschule Hannover

Hanover, 30625, Germany

RECRUITING

SLK-Kliniken Heilbronn GmbH;Klinik für Innere Medizin III

Heilbronn, 74078, Germany

RECRUITING

Praxis für Hämatologie, Onkologie und Palliativmedizin

Mönchengladbach, 41066, Germany

RECRUITING

Klinikum am Steinenberg / Ermstalklinik

Reutlingen, 72764, Germany

RECRUITING

Katharinenhospital Stuttgart

Stuttgart, 70174, Germany

RECRUITING

Marien-Hospital Wesel

Wesel, 46483, Germany

RECRUITING

General Hospital "G.Papanikolaou"

Asvestochóri, 570 10, Greece

RECRUITING

Henri Dunant Hospital

Athens, 115 26, Greece

RECRUITING

Alexandras General Hospital of Athens

Athens, 115 28, Greece

RECRUITING

Metropolitan Hospital Fourth Oncology Clinic

Faliro, 185 47, Greece

RECRUITING

Bioclinic Thessaloniki

Thessaloniki, 546 22, Greece

RECRUITING

Orszagos Onkologiai Intezet

Budapest, 1122, Hungary

RECRUITING

Bács-Kiskun Vármegyei Oktatókórház

Kecskemét, 6000, Hungary

RECRUITING

Pécsi Tudományegyetem

Pécs, 7623, Hungary

RECRUITING

Manipal Hospital

Bangalore, Karnataka, 560017, India

RECRUITING

HealthCare Global Enterprises Limited

Banglore, Karnataka, 560027, India

RECRUITING

Tata Memorial Hospital

Mumbai, Maharashtra, 400012, India

RECRUITING

MOC Cancer Care & Research Centre (Unit of Cellcure Cancer Centre Pvt Ltd)

Mumbai, Maharashtra, 400036, India

RECRUITING

Bhaktivedanta Hospital and research institute

Thane, Maharashtra, 401107, India

RECRUITING

Max Super Speciality Hospital

New Delhi, National Capital Territory of Delhi, 110017, India

RECRUITING

Apollo Hospitals

Chennai, Tamil Nadu, 600035, India

RECRUITING

Indo-American Cancer Hospital & Research Center

Hyderabad, Telangana, 500034, India

RECRUITING

Mid-Land Regional Hospital Tullamore

CO Offaly, R35 NY51, Ireland

RECRUITING

Adelaide & Meath Hospital, Dublin, Incorporating the National Children's Hospital

Dublin, 24, Ireland

RECRUITING

St Vincent'S Uni Hospital

Dublin, 4, Ireland

RECRUITING

St James's Hospital

Dublin, 8, Ireland

RECRUITING

Beacon Hospital

Dublin, D18 AK68, Ireland

RECRUITING

Hadassah University Hospital - Ein Kerem

Jerusalem, 9112001, Israel

RECRUITING

Sourasky / Ichilov Hospital

Tel Aviv, 6423906, Israel

RECRUITING

American University of Beirut - Medical Center

Beirut, 1107 2020, Lebanon

RECRUITING

Hotel Dieu de France

Beirut, 2063 1111, Lebanon

RECRUITING

Hammoud Hospital

Saida, 6520, Lebanon

RECRUITING

ONCARE Viaducto Napoles

Mexico City, Mexico CITY (federal District), 03810, Mexico

RECRUITING

Clínica Integral Internacional de Oncología S de RL de CV

Puebla City, Mexico CITY (federal District), Mexico

RECRUITING

The American British Cowdray Hospital/ Hospital Abc

Mexico City, 01120, Mexico

RECRUITING

Cebu Doctors' University Hospital

Cebu City, 6000, Philippines

RECRUITING

Metro Davao Medical and Research Center

Davao City, 8000, Philippines

RECRUITING

St Lukes Medical Center

Quezon City, 1102, Philippines

RECRUITING

Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie

Warsaw, 02-781, Poland

ACTIVE NOT RECRUITING

Hospital da Luz

Lisbon, 1500-650, Portugal

WITHDRAWN

Hospital CUF Porto

Porto, 4100-180, Portugal

RECRUITING

IPO do Porto

Porto, 4200-072, Portugal

RECRUITING

National Guard King Abdulaziz Medical City

Riyadh, 11426, Saudi Arabia

RECRUITING

University Hospital Medical Center Bezanijska kosa

Belgrade, 11080, Serbia

RECRUITING

Oncomed-System

Belgrade, Serbia

RECRUITING

SIRIUS Medical

Belgrade, Serbia

RECRUITING

Special hospital for internal diseases Vesalius

Belgrade, Serbia

RECRUITING

Oncology Institute of Vojvodina

Kamenitz, 21204, Serbia

RECRUITING

Narodny Onkologicky Ustav

Bratislava, 833 10, Slovakia

RECRUITING

University Clinic Golnik

Golnik, 4204, Slovenia

RECRUITING

Institute of Oncology Ljubljana

Ljubljana, 1000, Slovenia

RECRUITING

IATROS International

Bloemfontein, 9301, South Africa

RECRUITING

Linksfield Oncology Inc.

Johannesburg, 2192, South Africa

RECRUITING

Medical Oncology Centre of Rosebank

Johannesburg, 2196, South Africa

RECRUITING

Wilgers Oncology Centre

Pretoria, 0001, South Africa

RECRUITING

Hospital Universitario Son Espases

Palma de Mallorca, Balearic Islands, 07014, Spain

RECRUITING

Clinica Universitaria de Navarra

Pamplona, Navarre, 31008, Spain

WITHDRAWN

Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico

Jaén, 23007, Spain

RECRUITING

Hospital Clinico Universitario Virgen de la Victoria;Servicio de Oncologia

Málaga, 29011, Spain

RECRUITING

Hospital Universitario Miguel Servet

Zaragoza, 50009, Spain

RECRUITING

Chang Gung Medical Foundation - Kaohsiung

Kaohisung, 833, Taiwan

RECRUITING

Taipei Veterans General Hospital

Taipei, 112, Taiwan

RECRUITING

Chung Gung Memorial Hospital

Taoyuan County, 333, Taiwan

RECRUITING

Chulalongkorn Hospital

Bangkok, 10330, Thailand

RECRUITING

Faculty of Med. Siriraj Hosp.

Bangkok, 10700, Thailand

RECRUITING

Medicana International Zincirlikuyu Hospital

Istanbul, Enter Text, 34394, Turkey (Türkiye)

RECRUITING

Memorial Ankara Hastanesi

Ankara, 06520, Turkey (Türkiye)

RECRUITING

Trakya University Medical Faculty

Edirne, 22030, Turkey (Türkiye)

RECRUITING

Ba?c?lar Medipol Mega Üniversite Hastanesi

Istanbul, 34214, Turkey (Türkiye)

RECRUITING

Medicana International Atasehir Hospital

Istanbul, 34750, Turkey (Türkiye)

RECRUITING

Medicana International Izmir Hospital

Izmir, 35170, Turkey (Türkiye)

RECRUITING

Ac?badem Maslak Hastanesi Büyükdere

Sar?yer/?stanbul, 34457, Turkey (Türkiye)

RECRUITING

Ac?badem Adana Hospital, Oncology Department

Seyhan/Adana, 01130, Turkey (Türkiye)

RECRUITING

Tawam Hospital

Al Ain City, 15258, United Arab Emirates

RECRUITING

Mediclinic City Hospital

Dubai, United Arab Emirates

RECRUITING

Blackpool Victoria Hospital

Blackpool, FY3 8NR, United Kingdom

RECRUITING

Bristol Haematology and Oncology centre

Bristol, BS2 8ED, United Kingdom

RECRUITING

Royal Sussex County Hospital

Eastbourne, BN2 1ES, United Kingdom

RECRUITING

Royal Devon & Exeter Hospital

Exeter, EX2 5DW, United Kingdom

RECRUITING

Gloucestershire Royal Hospital

Gloucester, GL1 3NN, United Kingdom

RECRUITING

Royal Surrey County Hospital

Guildford, GU2 7XX, United Kingdom

RECRUITING

St Georges University Hospitals NHS Foundation Trust

London, SW17 0RE, United Kingdom

RECRUITING

Freeman Hospital

New Castle Upon Tyne, NE7 7DN, United Kingdom

RECRUITING

Mount Vernon Hospital

Northwood, HA6 2RN, United Kingdom

RECRUITING

Musgrove Park Hospital

Somerset, TA1 5DA, United Kingdom

RECRUITING

Kings Mill Hospital

Sutton in Ashfield, NG17 4JL, United Kingdom

RECRUITING

Torbay Hospital

Torquay, TQ2 7AA, United Kingdom

RECRUITING

Hanoi Oncology Hospital

Hanoi, 100000, Vietnam

RECRUITING

K hospital

Hanoi, 100000, Vietnam

RECRUITING

Ho Chi Minh City Oncology Hospital

Ho Chi Minh City, Vietnam

RECRUITING

Related Publications (1)

• Dienstmann R, Hackshaw A, Blay JY, Le Tourneau C. Core variables for real-world clinicogenomic data collection in precision oncology. ESMO Real World Data Digit Oncol. 2025 Feb 27;7:100117. doi: 10.1016/j.esmorw.2025.100117. eCollection 2025 Mar.

  PMID: 41647341 DERIVED

Related Links

• Related Info

Study Officials

• Clinical Trials

  Hoffmann-La Roche

  STUDY DIRECTOR

Central Study Contacts

Reference Study ID # MX39897 https://forpatients.roche.com/

CONTACT

888-662-6728; global-roche-genentech-trials@gene.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 25, 2020
• First Posted: August 27, 2020
• Study Start: August 27, 2020
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: May 5, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will share

Locations

TW (3); ES (5); LE (3); BR (5); SA (1); PL (1); TU (8); AR (2); GB (12); SE (5); SL (1); CO (6); ME (3); DE (10); IE (5); AU (1); PH (3); ZA (4); GR (5); HU (3); IL (2); CA (2); CL (2); FR (22); VN (3); IN (8); PT (3); AE (2); TH (2); EG (1)