NCT04502056

Brief Summary

The aim of the study is to build off results from our first experiment (NCT04371419) , and test whether messages that acknowledge racial injustice on behalf of institutions affect the retention of knowledge and movement of beliefs and behavior with respect to Covid-19. The investigators will also test the effect of concordance of providers and whether highlighting the unequal burden of the disease has additional effects on knowledge, beliefs and behavior regarding covid-19. The sample will include African American and white adult Americans and oversample those with less than a college degree.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20,460

participants targeted

Target at P75+ for not_applicable covid19

Timeline
Completed

Started Aug 2020

Shorter than P25 for not_applicable covid19

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 2, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 6, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

August 7, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 6, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 6, 2020

Completed
11 months until next milestone

Results Posted

Study results publicly available

July 27, 2021

Completed
Last Updated

July 27, 2021

Status Verified

July 1, 2021

Enrollment Period

1 month

First QC Date

August 2, 2020

Results QC Date

May 28, 2021

Last Update Submit

July 24, 2021

Conditions

Outcome Measures

Primary Outcomes (10)

  • Incidence Rate for Knowledge Gaps: Control vs. Any Intervention

    Participants were asked to identify ways to prevent COVID-19 spread and identify four common symptoms. The incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 10.

    The outcome was measured immediately following the intervention in the baseline survey.

  • Incidence Rate for Knowledge Gaps: Control vs. Any Intervention - Follow up

    Participants were asked to identify ways to prevent COVID-19 spread and identify four common symptoms. Incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 10.

    The outcome was measured at a follow-up within 2 weeks following the intervention

  • Incidence Rate for Information-seeking Behavior: Control vs. Any Intervention

    Participants were offered the option of requesting additional information on COVID-19 related resources by clicking on up to five links that included more content. We measured "information seeking behavior" as the number of links for which participants expressed interest, a count variable between 0 (lowest information seeking behavior) and 5 (greatest information seeking behavior). Incidence rate for interest in links is the count of links demanded divided by the maximum possible count: 5.

    The outcome was measured immediately following the intervention in the baseline survey.

  • Incidence Rate - Safety Gap Score: Control vs. Any Intervention

    Participants were asked about how often they engaged in four behaviors of interest: if they wore a mask indoors/outdoors; if they washed their hands; if they followed social distancing guidelines. The safety gap index takes values of 0 (if a participant reported that they always practiced the four behaviors of interest) up to 4 (none). Incidence rate for safety gaps is the count of safety gaps divided by the maximum possible count: 4.

    The outcome was measured at a follow-up within 2 weeks following the intervention.

  • Willingness to Pay (WTP) for Masks: Control vs. Any Intervention

    WTP: the participants will be asked to choose between two masks vs an unrestricted gift card. They will be asked what amount of gift card would make them just as happy to receive two mask versus the gift card.

    The outcome was measured immediately following the intervention in the baseline survey.

  • Incidence Rate Ratio (IRR) - Knowledge Gap

    Participants were asked to identify ways to prevent COVID-19 spread and identify four common symptoms. The incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 10. The incidence rate ratio compares the incidence rate of participants in Arm A vs. Arm B within the intervention group (i.e. those who received covid-19-related videos), within in the control group (i.e. those who saw placebo videos), or across the intervention and control group. Arms A and B are described in each Arm/Group Title. The overall number of participants analyzed is all equal across 6 arms/groups because the outcome measure data presented below came from a single negative binomial regression.

    The outcome was measured immediately following the intervention in the baseline survey.

  • Incidence Rate Ratio (IRR) - Knowledge Gap - Follow up

    Participants were asked to identify ways to prevent COVID-19 spread and identify four common symptoms. The incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 10. The incidence rate ratio compares the incidence rate of participants in Arm A vs. Arm B within the intervention group (i.e. those who received covid-19-related videos), within in the control group (i.e. those who saw placebo videos), or across the intervention and control group. Arms A and B are described in each Arm/Group Title. The overall number of participants analyzed is all equal across 6 arms/groups because the outcome measure data presented below came from a single negative binomial regression.

    The outcome was measured at a follow-up within 2 weeks following the intervention

  • Incidence Rate Ratio (IRR) - Information-seeking Behavior

    Participants were offered the option of requesting additional information on COVID-19 related resources by clicking on up to 5 links that included more content. We measured "information seeking behavior" as the number of links for which participants expressed interest, a count variable between 0 (lowest information seeking behavior) and 5 (greatest information seeking behavior). Incidence rate for interest in links is the count of links demanded divided by the maximum possible count: 5. The incidence rate ratio compares the incidence rate of participants in Arm A vs. Arm B within the intervention group (i.e. those who received covid-19-related videos), within in the control group (i.e. those who saw placebo videos), or across the intervention and control group. Arms A and B are described in each Arm/Group Title. The overall number of participants analyzed is all equal across 6 arms/groups because the outcome measure data presented below came from a single negative binomial regression.

    The outcome was measured immediately following the intervention in the baseline survey.

  • Incidence Rate Ratio (IRR) - Safety Gap Score

    Participants were asked about how often they engaged in four behaviors of interest: if they wore a mask indoors/outdoors; if they washed their hands; if they followed social distancing guidelines. The safety gap index takes values of 0 (if a participant reported that they always practiced the four behaviors of interest) up to 4 (none). Incidence rate for safety gaps is the count of safety gaps divided by the maximum possible count: 4. The incidence rate ratio compares the incidence rate of participants in Arm A vs. Arm B within the intervention group (i.e. those who received covid-19-related videos), within in the control group (i.e. those who saw placebo videos), or across the intervention and control group. Arms A and B are described in each Arm/Group Title. The overall number of participants analyzed is all equal across 6 arms/groups because the outcome measure data presented below came from a single negative binomial regression.

    The outcome was measured at a follow-up within 2 weeks following the intervention.

  • OLS Regression Coefficients - Willingness to Pay (WTP) for Masks

    WTP: the participants will be asked to choose between two masks vs an unrestricted gift card. They will be asked what amount of gift card would make them just as happy to receive two mask versus the gift card. The regression coefficients compares the incidence rate of participants in Arm A vs. Arm B within the intervention group (i.e. those who received covid-19-related videos), within in the control group (i.e. those who saw placebo videos), or across the intervention and control group. Arms A and B are described in each Arm/Group Title. The overall number of participants analyzed is all equal across 6 arms/groups because the outcome measure data presented below came from a single ordinary least squares (OLS) regression for WTP masks).

    The outcome was measured immediately following the intervention in the baseline survey.

Study Arms (12)

AMA RI - B- B - R

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging racial injustice read by an African American individual. The messenger / doctor in the follow-up AMA videos will also be African American - the message on Covid-19 will include information on the disproportionate impact on communities of color.

Behavioral: Acknowledgement Racial Injustice AMABehavioral: African American Sender AcknowledgementBehavioral: African American Sender in Informational Videos.Behavioral: Racial Inequality Highlighted

AMA RI - B - B - N

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging racial injustice read by an African American individual. The messenger / doctor in the follow-up AMA videos will also be African American - the message on Covid-19 will not include information on the disproportionate impact on communities of color.

Behavioral: Acknowledgement Racial Injustice AMABehavioral: African American Sender AcknowledgementBehavioral: African American Sender in Informational Videos.Behavioral: No Racial Inequality Highlighting

AMA RI - W - W - R

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging racial injustice read by a white individual. The messenger / doctor in the follow-up AMA videos will be white - the message on Covid-19 will include information on the disproportionate impact on communities of color.

Behavioral: Acknowledgement Racial Injustice AMABehavioral: Racial Inequality HighlightedBehavioral: White Sender in AcknowledgementBehavioral: White Sender in Informational Videos

AMA RI - W - W - N

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging racial injustice read by a white individual. The messenger / doctor in the follow-up AMA videos will be white - the message on Covid-19 will not include information on the disproportionate impact on communities of color.

Behavioral: Acknowledgement Racial Injustice AMABehavioral: White Sender in AcknowledgementBehavioral: White Sender in Informational VideosBehavioral: No Racial Inequality Highlighting

AMA DP - B- B - R

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging drug pricing read by an African American individual. The messenger / doctor in the follow-up AMA videos will also be African American - the message on Covid-19 will include information on the disproportionate impact on communities of color .

Behavioral: African American Sender AcknowledgementBehavioral: African American Sender in Informational Videos.Behavioral: Racial Inequality HighlightedBehavioral: AMA Acknowledgement Drug Pricing

AMA DP - B- B - N

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging drug pricing read by an African American individual. The messenger / doctor in the follow-up AMA videos will also be African American - the message on Covid-19 will not include information on the disproportionate impact on communities of color.

Behavioral: African American Sender AcknowledgementBehavioral: African American Sender in Informational Videos.Behavioral: AMA Acknowledgement Drug PricingBehavioral: No Racial Inequality Highlighting

AMA DP - W- W - R

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging drug pricing read by a white individual. The messenger / doctor in the follow-up AMA videos will be white - the message on Covid-19 will include information on the disproportionate impact on communities of color.

Behavioral: Racial Inequality HighlightedBehavioral: AMA Acknowledgement Drug PricingBehavioral: White Sender in AcknowledgementBehavioral: White Sender in Informational Videos

AMA DP - W- W - N

EXPERIMENTAL

Respondents will be randomized to an AMA statement acknowledging drug pricing read by a white individual. The messenger / doctor in the follow-up AMA videos will be white - the message on Covid-19 will not include information on the disproportionate impact on communities of color.

Behavioral: AMA Acknowledgement Drug PricingBehavioral: White Sender in AcknowledgementBehavioral: White Sender in Informational VideosBehavioral: No Racial Inequality Highlighting

Control: AMA RI - B - B

PLACEBO COMPARATOR

Respondents will be randomized to an AMA statement acknowledging racial injustice read by an African American individual. The messenger / doctor in the follow-up AMA videos will also be African American - No message on Covid-19 will be shown. Acknowledgement Racial Injustice AMA: Investigators will examine whether acknowledgements of racial inequality are helpful towards improving knowledge retention and behaviors associated with the intervention among participants. In this arm, participants will receive a AMA statement on racial injustice. African American Sender Acknowledgement: Investigators will also vary the messenger of the acknowledgement sender. In this arm participants receive a African American sender in acknowledgment of AMA

Behavioral: Acknowledgement Racial Injustice AMABehavioral: African American Sender AcknowledgementBehavioral: African American Sender in Informational Videos.Behavioral: Placebo videos

Control: AMA RI - W - W

PLACEBO COMPARATOR

Respondents will be randomized to an AMA statement acknowledging racial injustice read by a white individual. The messenger / doctor in the follow-up AMA videos will also be white - No message on Covid-19 will be shown. Acknowledgement Racial Injustice AMA: Investigators will examine whether acknowledgements of racial inequality are helpful towards improving knowledge retention and behaviors associated with the intervention among participants. In this arm, participants will receive a AMA statement on racial injustice. White Sender Acknowledgement: Investigators will also vary the messenger of the acknowledgement sender. In this arm participants receive a white sender in acknowledgment of AMA

Behavioral: Acknowledgement Racial Injustice AMABehavioral: White Sender in AcknowledgementBehavioral: White Sender in Informational VideosBehavioral: Placebo videos

Control: AMA DP - B - B

PLACEBO COMPARATOR

Respondents will be randomized to an AMA statement acknowledging drug pricing read by an African American individual. The messenger / doctor in the follow-up AMA videos will also be African American - No message on Covid-19 will be shown. African American Sender Acknowledgement: Investigators will also vary the messenger of the acknowledgement sender. In this arm participants receive a African American sender in acknowledgment of AMA AMA Acknowledgement Drug Pricing: Investigators will examine whether acknowledgements of racial inequality are helpful towards improving knowledge retention and behaviors associated with the intervention among participants. In this arm, participants receive AMA information on drug pricing

Behavioral: African American Sender AcknowledgementBehavioral: African American Sender in Informational Videos.Behavioral: AMA Acknowledgement Drug PricingBehavioral: Placebo videos

Control: AMA DP - W - W

PLACEBO COMPARATOR

Respondents will be randomized to an AMA statement acknowledging drug pricing read by a white individual. The messenger / doctor in the follow-up AMA videos will also be white - No message on Covid-19 will be shown. White Sender Acknowledgement: Investigators will also vary the messenger of the acknowledgement sender. In this arm participants receive a white sender in acknowledgment of AMA AMA Acknowledgement Drug Pricing: Investigators will examine whether acknowledgements of racial inequality are helpful towards improving knowledge retention and behaviors associated with the intervention among participants. In this arm, participants receive AMA information on drug pricing

Behavioral: AMA Acknowledgement Drug PricingBehavioral: White Sender in AcknowledgementBehavioral: White Sender in Informational VideosBehavioral: Placebo videos

Interventions

Investigators will examine whether acknowledgements of racial inequality are helpful towards improving knowledge retention and behaviors associated with the intervention among participants. In this arm, participants will receive a AMA statement on racial injustice.

AMA RI - B - B - NAMA RI - B- B - RAMA RI - W - W - NAMA RI - W - W - RControl: AMA RI - B - BControl: AMA RI - W - W

Investigators will also vary the messenger of the acknowledgement sender. In this arm participants receive a African American sender in acknowledgment of AMA

AMA DP - B- B - NAMA DP - B- B - RAMA RI - B - B - NAMA RI - B- B - RControl: AMA DP - B - BControl: AMA RI - B - B

Investigators will vary the sender of the informational covid-19 videos. In this arm, participants receive a African American sender in informational videos.

AMA DP - B- B - NAMA DP - B- B - RAMA RI - B - B - NAMA RI - B- B - RControl: AMA DP - B - BControl: AMA RI - B - B

Investigators will include information on race-specific covid-19 cases and deaths in one variation in the messaging. In this arm, participants receive disproportionate race-specific Covid-19 facts

AMA DP - B- B - RAMA DP - W- W - RAMA RI - B- B - RAMA RI - W - W - R

Investigators will examine whether acknowledgements of racial inequality are helpful towards improving knowledge retention and behaviors associated with the intervention among participants. In this arm, participants receive AMA information on drug pricing

AMA DP - B- B - NAMA DP - B- B - RAMA DP - W- W - NAMA DP - W- W - RControl: AMA DP - B - BControl: AMA DP - W - W

Investigators will also vary the messenger of the acknowledgement sender. In this arm, participants receive a white sender in the acknowledgement

AMA DP - W- W - NAMA DP - W- W - RAMA RI - W - W - NAMA RI - W - W - RControl: AMA DP - W - WControl: AMA RI - W - W

Investigators will vary the messenger of the informational covid-19 videos. In this arm, participants receive white sender in the informational video

AMA DP - W- W - NAMA DP - W- W - RAMA RI - W - W - NAMA RI - W - W - RControl: AMA DP - W - WControl: AMA RI - W - W

In this arm, the disproportionate burden of Covid-19 on communities of color will not be highlighted

AMA DP - B- B - NAMA DP - W- W - NAMA RI - B - B - NAMA RI - W - W - N
Placebo videosBEHAVIORAL

Videos not related to covid-19 will be shown

Control: AMA DP - B - BControl: AMA DP - W - WControl: AMA RI - B - BControl: AMA RI - W - W

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adults who self-identify as African American or white.
  • an oversample of individuals with less than a college education

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

JPAL North America

Cambridge, Massachusetts, 02138, United States

Location

Related Publications (1)

  • Torres C, Ogbu-Nwobodo L, Alsan M, Stanford FC, Banerjee A, Breza E, Chandrasekhar AG, Eichmeyer S, Karnani M, Loisel T, Goldsmith-Pinkham P, Olken BA, Vautrey PL, Warner E, Duflo E; COVID-19 Working Group. Effect of Physician-Delivered COVID-19 Public Health Messages and Messages Acknowledging Racial Inequity on Black and White Adults' Knowledge, Beliefs, and Practices Related to COVID-19: A Randomized Clinical Trial. JAMA Netw Open. 2021 Jul 1;4(7):e2117115. doi: 10.1001/jamanetworkopen.2021.17115.

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Limitations and Caveats

1\. It was conducted online, and the participants may not be representative of the population with less than a college degree, since they have access to the internet and are used to participating in online studies; 2. Participants' preventive health behaviors were not directly observed; 3. Outcomes might be subject to social desirability bias.

Results Point of Contact

Title
Tristan Loisel
Organization
JPAL North America

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Abdul Latif Jameel Professor of Poverty Alleviation and Development Economics, MIT; Co-Director, Abdul Latif Jameel Poverty Action Lab

Study Record Dates

First Submitted

August 2, 2020

First Posted

August 6, 2020

Study Start

August 7, 2020

Primary Completion

September 6, 2020

Study Completion

September 6, 2020

Last Updated

July 27, 2021

Results First Posted

July 27, 2021

Record last verified: 2021-07

Locations