NCT04506268

Brief Summary

In order to safely and effectively reopen businesses and universities across the US, institutions will need to develop approaches to rapidly identify COVID-19 cases and manage their spread while balancing program effectiveness, feasibility, costs, and scalability. The investigators will evaluate the implementation of a COVID-19 screening program that coordinates several existing systems at the University of Pennsylvania including saliva-based viral testing and test different outreach strategies (opt-in vs opt-out) to improve program enrollment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
412

participants targeted

Target at P75+ for not_applicable covid19

Timeline
Completed

Started Sep 2020

Shorter than P25 for not_applicable covid19

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 7, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 10, 2020

Completed
1 month until next milestone

Study Start

First participant enrolled

September 9, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2020

Completed
Last Updated

March 11, 2021

Status Verified

March 1, 2021

Enrollment Period

2 months

First QC Date

August 7, 2020

Last Update Submit

March 10, 2021

Conditions

Keywords

COVID-19Coronavirusopt-inopt-outbehavioral science

Outcome Measures

Primary Outcomes (1)

  • Proportion Enrolled

    The proportion of those invited that enroll in the study

    4 weeks

Secondary Outcomes (6)

  • Participant Age

    4 weeks

  • Participant Sex

    4 weeks

  • Participant Race/Ethnicity

    4 weeks

  • Participant Income

    4 weeks

  • Participant Education

    4 weeks

  • +1 more secondary outcomes

Study Arms (2)

Opt-in Recruitment Email

EXPERIMENTAL

Participants will receive a recruitment email that describes the objectives of a new COVID-19 voluntary screening program, and invites them to enroll.

Behavioral: Opt-in Recruitment Email

Opt-out Recruitment Email

EXPERIMENTAL

Participants will receive a recruitment email that describes the objectives of a new COVID-19 voluntary screening program, and informs them that they have been conditionally enrolled.

Behavioral: Opt-out Recruitment Email

Interventions

Behaviorally informed, opt-out framed recruitment email

Opt-out Recruitment Email

Standard, opt-in framed recruitment email

Opt-in Recruitment Email

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • University of Pennsylvania staff, faculty, and trainees that have returned to work on campus who have been identified by leadership at the University of Pennsylvania Perelman School of Medicine.

You may not qualify if:

  • Participants will not be eligible for the study if they identify any reason they are unable to participate in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Penn Medicine

Philadelphia, Pennsylvania, 19103, United States

Location

MeSH Terms

Conditions

COVID-19Coronavirus Infections

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Mitesh S Patel, MD

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 7, 2020

First Posted

August 10, 2020

Study Start

September 9, 2020

Primary Completion

October 30, 2020

Study Completion

October 30, 2020

Last Updated

March 11, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Locations