NCT04489394

Brief Summary

Prospective study, not randomised, non-interventional, monocentric, investigating an intended patient cohort of 60 patients already operated on the cervical spine due to degenerative disc disease of the cervical spine down to the first thoracolumbar VBR (C2-T1), who received a Quintex plate for stabilisation

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 11, 2019

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 18, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 18, 2020

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

July 24, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 28, 2020

Completed
Last Updated

April 9, 2024

Status Verified

April 1, 2024

Enrollment Period

3 months

First QC Date

July 24, 2020

Last Update Submit

April 5, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Clinical Results measured by Neck Disability Index (NDI)

    The NDI is designed to measure neck-specific disability. The questionnaire has 10 items to measure patient-reported disability secondary to neck pain and activities of daily living including personal care, lifting, reading, headaches, concentration, work status, driving, sleeping and recreation and patients rate their status from 0 (best) to 5 (worst imaginable). Individual item responses are summed to a total score, where 0 points indicate no activity limitations and 50 points indicate complete activity limitation.

    One retrospective visit, between one and approx. five years post-op.

Secondary Outcomes (7)

  • Neck and arm pain

    One retrospective visit, between one and approx. five years post-op.

  • Patient satisfaction

    One retrospective visit, between one and approx. five years post-op.

  • Quality of life measured by EQ-5D-5L

    One retrospective visit, between one and approx. five years post-op.

  • Dysphagia assessment

    One retrospective visit, between one and approx. five years post-op.

  • Complications

    One retrospective visit, between one and approx. five years post-op.

  • +2 more secondary outcomes

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

adult patients

You may qualify if:

  • \- all patients who received a Quintex® Anterior Cervical Plate since 2014 until approx. end 2018 (minimum Follow-up is one year) in the study center

You may not qualify if:

  • Patient informed consent not signed
  • Patients living outside a radius of 80 km around the study center

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Katholisches Klinikum Koblenz

Koblenz, 56073, Germany

Location

Related Publications (1)

  • Bruchmann B, Kilian F. Follow-up of a new titanium cervical plate for fusion of the cervical spine. Orthop Rev (Pavia). 2023 Oct 12;15:84651. doi: 10.52965/001c.84651. eCollection 2023.

MeSH Terms

Conditions

Intervertebral Disc DegenerationSpondylolisthesisWounds and InjuriesSpinal StenosisSpondylosis

Condition Hierarchy (Ancestors)

Spinal DiseasesBone DiseasesMusculoskeletal DiseasesSpondylolysis

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 24, 2020

First Posted

July 28, 2020

Study Start

November 11, 2019

Primary Completion

February 18, 2020

Study Completion

February 18, 2020

Last Updated

April 9, 2024

Record last verified: 2024-04

Locations