NCT04477447

Brief Summary

Prospective, pure data collection of all CeSPACE 3D patients in selected centers (not interventional, multicenter)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
101

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2020

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 10, 2020

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 20, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

September 21, 2020

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 13, 2023

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 16, 2024

Completed
Last Updated

December 19, 2024

Status Verified

December 1, 2024

Enrollment Period

2.7 years

First QC Date

July 10, 2020

Last Update Submit

December 18, 2024

Conditions

Keywords

Cervical Vertebrae;Spondylolisthesis;Treatment Outcome;Interbody Fusion

Outcome Measures

Primary Outcomes (1)

  • Change of Neck Specific Disability measured by Neck Disability Index (NDI)

    The NDI is designed to measure neck-specific disability. The questionnaire has 10 items to measure patient-reported disability secondary to neck pain and activities of daily living including personal care, lifting, reading, headaches, concentration, work status, driving, sleeping and recreation and patients rate their status from 0 (best) to 5 (worst imaginable). Individual item responses are summed to a total score, where 0 points indicate no activity limitations and 50 points indicate complete activity limitation.

    preoperative, 12 months postoperative

Secondary Outcomes (6)

  • JOA score

    preoperatively and at one follow-up- assessment after a minimum of one year postoperatively

  • Pain (VAS)

    preoperatively and at one follow-up- assessment after a minimum of one year postoperatively

  • development of EQ-5D-5L

    preoperatively and at one follow-up- assessment after a minimum of one year postoperatively

  • development of radiological outcome

    preoperatively and at one follow-up- assessment after a minimum of one year postoperatively

  • Rate of AE/SAEs

    preoperatively, intraoperatively and at one follow-up- assessment after a minimum of one year postoperatively

  • +1 more secondary outcomes

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

adult patients

You may qualify if:

  • Patient is minimum 18 years old
  • Written informed consent for the documentation of clinical and radiological results
  • Patient's indication according to IFU
  • Patient is not pregnant

You may not qualify if:

  • Patient is not willing or able to participate at the follow-up examination

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Katholisches Klinikum Koblenz

Koblenz, 56073, Germany

Location

Sana Kliniken Sommerfeld

Kremmen, 16766, Germany

Location

MeSH Terms

Conditions

Spondylolisthesis

Condition Hierarchy (Ancestors)

SpondylolysisSpondylosisSpinal DiseasesBone DiseasesMusculoskeletal Diseases

Study Officials

  • Stefan Nikolaus Kroppenstedt, Dr. med.

    Abteilung für Wirbelsäulenchirurgie Sana Kliniken Sommerfeld

    PRINCIPAL INVESTIGATOR
  • Francis Kilian, Dr. med.

    Katholisches Klinikum Koblenz

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 10, 2020

First Posted

July 20, 2020

Study Start

September 21, 2020

Primary Completion

June 13, 2023

Study Completion

April 16, 2024

Last Updated

December 19, 2024

Record last verified: 2024-12

Locations