Survival and 30-days Hospital Outcome in COVID-19 Patients in Upper Egypt

NCT04488588 | Completed

• 1 other identifier: AssiutU17
• Study Type: observational
• Target: 1,064
• Locations: 1 country
• Sites: 2

Brief Summary

Through history, there have been plenty of pandemics however; the social response to corona virus disease (COVID-19) is unparalleled. It is assessed that almost four billion individuals are living in social segregation during this mother of all pandemics. Initially described in China in December 2019, severe acute respiratory syndrome caused by corona virus 2 (SARS-CoV-2) has spread all over the world and by 18th July 2020- there was an emergent figure of 13,824,739 confirmed cases and 591.666 losses reported to the WHO. To date, Egypt reported slightly over 82,000 confirmed COVID-19 cases with 3858 deaths. The new pandemic is injuring not only health organizations of several countries but also the financial prudence universal. Defining the clinical features and associated outcomes of patients diagnosed with coronavirus disease (COVID-19) is fundamental to improving our understanding and adequate management of this illness. Several articles have recently been published, describing the clinical features and outcomes of retrospective individuals with COVID-19

Conditions

Covid19; Coronavirus Disease; SARS-CoV-2

Keywords

COVID-19; Survival; 30- Days Hospital outcome; outcome

Outcome Measures

Primary Outcomes (2)

• number of co-morbidities in hospitalized patients with COVID-19

  Determinants of survival in studied covid-19 patients admitted to hospitals

  one month

• causes of ICU admission

  Determinants of ICU admission in hospitalized patients with COVID-19

  one month

Interventions

Kaplan Meier analysis OTHER

Kaplan Meier survival analysis was conducted to calculate the cumulative overall survival rates using Log Rank test for comparison between age groups

Eligibility Criteria

• Age: 36 Years - 63 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All cases had confirmed COVID-19 infection (based on PCR, chest HRCT, CBC, CRP, Ferritin levels) and received standardized treatment protocols of Ministry of Health and Population based on disease severity.

You may qualify if:

• This study included 1064 patients consecutively admitted to isolation hospitals in Upper Egypt during the period from 22 March to 23 June 2020

You may not qualify if:

• only hospitalized confirmed cases of COVID-19 were included.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (2)

AssiutU

Asyut, 71111, Egypt

Location

Aliae Mohamed-Hussein

Asyut, 71515, Egypt

Location

MeSH Terms

Conditions

COVID-19

Interventions

Kaplan-Meier Estimate

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Survival Analysis; Statistics as Topic; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Aliae Mohamed-Hussein, MD

  Assiut University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Pulmonology

Study Record Dates

• First Submitted: July 24, 2020
• First Posted: July 28, 2020
• Study Start: March 15, 2020
• Primary Completion: May 1, 2020
• Study Completion: July 1, 2020
• Last Updated: July 28, 2020

Record last verified: 2020-07

Locations

EG (2)