NCT04561154

Brief Summary

Since December 2019, China and then the rest of the world have been affected by the rapid spread of a new coronavirus infection called SARS-CoV-2 (severe acute respiratory syndrome coronavirus), the clinical expression of which is called Covid-19 (Coronavirus Disease 2019). It is estimated that around 20% of symptomatic patients will be severe enough to warrant hospitalization, of which around 5% will be in intensive care. Organ damage is multiple in Covid infection: respiratory, digestive, renal, neurological, cardiovascular due to the infection or its care. There is also a psychological and social impact of the infection or of the care that should be measured. In this context, investigator will assess the physical and psychological complaints of patients who have presented a severe form of SARS-CoV-2 infection. The final objective being to identify the needs to offer follow-up adapted to this emerging pathology.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
134

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 11, 2020

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 9, 2020

Completed
14 days until next milestone

First Posted

Study publicly available on registry

September 23, 2020

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 11, 2021

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

June 11, 2022

Completed
Last Updated

March 9, 2022

Status Verified

March 1, 2022

Enrollment Period

1 year

First QC Date

September 9, 2020

Last Update Submit

March 8, 2022

Conditions

Keywords

SARS-COV2functionnal complaintssequel

Outcome Measures

Primary Outcomes (4)

  • Identify functionnal and psychosocial complaints

    the prevalence of functional complaints and psycho-social complaints (justifying additional investigations in patients hospitalized for Covid-19 infection 3 months maximum after discharge from hospital) will be assessed by questionnaire "Modified Medical Research Council"

    3 months after last hospitalization

  • Identify functionnal and psychosocial complaints

    the prevalence of functional complaints and psycho-social complaints (justifying additional investigations in patients hospitalized for Covid-19 infection 3 months maximum after discharge from hospital) will be assessed by questionnaire "Medical Outcome Study Short Form 36 (MOS SF-36)"

    3 months after last hospitalization

  • Identify functionnal and psychosocial complaints

    the prevalence of functional complaints and psycho-social complaints (justifying additional investigations in patients hospitalized for Covid-19 infection 3 months maximum after discharge from hospital) will be assessed by FRIED criteria

    3 months after last hospitalization

  • Identify functionnal and psychosocial complaints

    the prevalence of functional complaints and psycho-social complaints (justifying additional investigations in patients hospitalized for Covid-19 infection 3 months maximum after discharge from hospital) will be assessed by questionnaire "Hospital Anxiety and Depression Scale (HADS)"

    3 months after last hospitalization

Secondary Outcomes (12)

  • description of functionnal and psychosocial complaints

    3 months after last hospitalization

  • description of functionnal and psychosocial complaints

    3 months after last hospitalization

  • description of functionnal and psychosocial complaints

    3 months after last hospitalization

  • description of functionnal and psychosocial complaints

    3 months after last hospitalization

  • Identify the factors favoring the persistence of complaints

    3 months after last hospitalization

  • +7 more secondary outcomes

Study Arms (1)

patient hospitalized between march 1 and june 30, 2020

EXPERIMENTAL

patient hospitalized between march 1 and june 30, 2020

Other: questionnaire

Interventions

three months after hospitalization, a questionnaire will be sent to patients. If necessary, patient will be seen in consultation of geriatry, otorhinolaryngology, pneumology, neuropsychology

patient hospitalized between march 1 and june 30, 2020

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient hospitalized for severe Covid-19 infection between March 1 and June 30, 2020 in a conventional unit, intensive care unit, at the Centre hospitalier du Mans and alive at the time of the investigation at 2 to 3 months
  • Patient having given their express consent, after having received the research information letter upon discharge from hospital or having given their express consent after sending the information letter
  • Age ≥ 18 years
  • Patient having contracted a SARS-CoV-2 infection proved by RT-PCR and / or retrospective serology and / or a Covid-19 syndrome with suggestive chest scanner (during the period from March 1, 2020 to June 30, 2020)

You may not qualify if:

  • Patient opposition to participate in the cohort
  • Non-French speaking patient
  • Patients who cannot read or write
  • Patient subject to a protective measure
  • Patient not affiliated to a social security or equivalent health insurance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Hospitalier du Mans

Le Mans, 72000, France

RECRUITING

MeSH Terms

Conditions

COVID-19

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Central Study Contacts

Christelle JADEAU

CONTACT

Hikombo HITOTO

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 9, 2020

First Posted

September 23, 2020

Study Start

June 11, 2020

Primary Completion

June 11, 2021

Study Completion

June 11, 2022

Last Updated

March 9, 2022

Record last verified: 2022-03

Locations