Novel COVID-19, A National Analysis

NCT04413045 | Completed

• 1 other identifier: Novel COVID-19 Prevalence
• Study Type: observational
• Target: 61
• Locations: 1 country
• Sites: 1

Brief Summary

Pneumonia is a form of acute respiratory tract infection (ARTI) that affects the lungs. When an individual has pneumonia, the alveoli in the lungs are filled with pus and fluid, which makes breathing painful and limits oxygen intake. Pneumonia has many possible causes, but the most common are bacteria and viruses but nowadays there is a pandemic spread from novel corona virus which cause corona virus disease 2019 (COVID-19). Corona virus comprises of a large family of viruses that are common in human beings as well animals (camels, cattle, cats, and bats). There are seven different strains of corona virus. Sometimes corona virus from animals infect people and spread further via human to human transmission such as with MERS-CoV, SARS-CoV, and now with this COVID-19 (Corona disease 2019). The virus that causes COVID-19 is designated as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2); previously, referred to as 2019-nCoV. On Towards December 2019, this novel corona virus was identified as a cause of upper and lower respiratory tract infections in Wuhan, a city in the Hubei Province of China. It rapidly spread, resulting in an epidemic throughout China and then gradually spreading to other parts of the world in pandemic proportions. It has affected almost every continent in this world. In February 2020, the World Health Organization designated the disease COVID-19, which stands for corona virus disease 2019. The Coronaviruses are a large family of single-stranded RNA viruses (+ssRNA) that can be isolated in different animal species. They have a crown-like appearance under an electron microscope (coronam is the Latin term for crown) due to the presence of spike glycoproteins on the envelope. These viruses can also infect humans and cause illness ranging from the common cold to more severe diseases such as MERS, SARS and now COVID-19. According to recent research, a spike mutation, which probably occurred in late November 2019, triggered jumping to humans.

Conditions

COVID-19

Outcome Measures

Primary Outcomes (1)

• Patient Prognosis Score

  The prognosis of COVID-19 patients at one quarantine hospital delivered to home, prolonged hospital stay, death.

  1 month

Secondary Outcomes (6)

• Oxygen Saturation

  14 days

• Laboratory Data

  14 days

• Radiological Features

  1 month

• Hospital Stay

  1 month

• Liver Function

  1 month

Study Arms (1)

C Group

All COVID-19 cases to be admitted in the assigned hospital with positive results of nasopharyngeal swab for SARS-CoV-2 during one-month duration.

Other: Prevalence of COVID-19

Interventions

Prevalence of COVID-19 OTHER

All COVID-19 cases to be admitted in the assigned hospital with positive results of nasopharyngeal swab for SARS-CoV-2 during one-month duration.

C Group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study is an investigator-initiated cross sectional trial to record, assess the clinical manifestations and prognosis of all COVID-19 cases to be admitted in the assigned hospital with positive results of nasopharyngeal swab for SARS-CoV-2 during one-month duration. The study aims To detect epidemiology, clinical and radiological presentation, laboratory findings, complications, duration needed to conversion from positive to negative PCR, duration of hospital stay and outcome of COVID-19 patients admitted in one quarantine hospital

You may qualify if:

• Any Age
• Any Sex
• non pregnant women
• RT-PCR positive for SARS-CoV-2

You may not qualify if:

• Patient Refusal
• Pregnancy
• patients stopped participation at anytime

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University Hospitals

Asyut, 71515, Egypt

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Mohamed F. Mostafa, MD

  membership/educator

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Anesthesia and Intensive Care

Study Record Dates

• First Submitted: June 1, 2020
• First Posted: June 2, 2020
• Study Start: May 20, 2020
• Primary Completion: July 28, 2020
• Study Completion: July 28, 2020
• Last Updated: August 4, 2020

Record last verified: 2020-08

Locations

EG (1)