NCT04450108

Brief Summary

This is a multi-center study to evaluate fractional exhaled nitric oxide (FeNO) measured with the Vivatmo pro in adult and pediatric subjects.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
122

participants targeted

Target at P50-P75 for not_applicable asthma

Timeline
Completed

Started Sep 2020

Shorter than P25 for not_applicable asthma

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 24, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 29, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

September 8, 2020

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 18, 2020

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 13, 2021

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

June 6, 2022

Completed
Last Updated

June 6, 2022

Status Verified

May 1, 2022

Enrollment Period

3 months

First QC Date

June 24, 2020

Results QC Date

April 12, 2022

Last Update Submit

May 11, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in FeNO Value

    Change in FeNO value before and after inhaled corticosteroid treatment

    14 days

Study Arms (1)

Test Cohort

EXPERIMENTAL

Subjects age 7 to 80 with asthma

Diagnostic Test: Vivatmo pro FeNO Test

Interventions

Vivatmo pro FeNO TestDIAGNOSTIC_TEST

Breath gas analysis

Also known as: Fractional exhaled nitric oxide (FeNo)
Test Cohort

Eligibility Criteria

Age7 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is 7 to 80 years of age.
  • Has asthma
  • Has been identified as a candidate for inhaled corticosteroid (ICS) treatment
  • Is willing and able to perform Vivatmo pro™ testing

You may not qualify if:

  • Subject has used corticosteroids prior to enrollment.
  • Subject has other current serious medical conditions
  • Subject has not been clinically stable for at least 2 weeks prior to the study
  • Subject is unwilling or unable to perform Vivatmo pro testing

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Clinical Research Center of Alabama

Birmingham, Alabama, 35209, United States

Location

Kern Research, Inc.

Bakersfield, California, 93301, United States

Location

Chesapeake Clinical Research, Inc.

White Marsh, Maryland, 21162, United States

Location

The Clinical Research Center, LLC

St Louis, Missouri, 63141, United States

Location

North Carolina Clinical Research

Raleigh, North Carolina, 27607, United States

Location

Allergy Asthma Research Institute

Waco, Texas, 76712, United States

Location

MeSH Terms

Conditions

Asthma

Interventions

Fractional Exhaled Nitric Oxide Testing

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

Breath TestsDiagnostic Techniques and ProceduresDiagnosis

Results Point of Contact

Title
Dr. Klaus Müller, Study director
Organization
Bosch Healthcare Solutions

Study Officials

  • Klaus Mueller

    Bosch Healthcare

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 24, 2020

First Posted

June 29, 2020

Study Start

September 8, 2020

Primary Completion

December 18, 2020

Study Completion

April 13, 2021

Last Updated

June 6, 2022

Results First Posted

June 6, 2022

Record last verified: 2022-05

Locations