Effects of Exercise Intensity on Energy Intake, Appetite and Enjoyment in Overweight and Obese Females

NCT04437550 | Completed

• 1 other identifier: 801776
• Study Type: interventional
• Target: 11
• Locations: 1 country
• Sites: 1

Brief Summary

Interval exercise involves short bouts of high intensity exercise interspersed with periods of lower intensity exercise. The benefit is that a shorter total duration of exercise may be required to achieve cardiovascular benefits similar to or even superior to traditional longer bouts of steady state endurance exercise. However how this type of exercise affects appetite and energy intake, particularly in overweight and obese females is not well known. This study involves two trials of exercise, one at high intensity and one at low intensity, followed by a buffet lunch, in overweight and obese females.

Conditions

Overweight and Obesity

Outcome Measures

Primary Outcomes (4)

• Change in energy expenditure

  caloric expenditure measured via indirect calorimetry

  immediately pre-breakfast, immediately pre-exercise, during exercise, and immediately post-exercise.

• Change in energy intake

  measured via standardized lunch

  immediately post exercise

• Change in appetite

  measured via circulating hormones leptin and acylated ghrelin

  immediately pre-breakfast, immediately post-breakfast, immediately post-exercise and immediately pre-lunch

• Change in subjective hunger

  via visual analogue scale 100 mm, higher scores indicate greater hunger

  baseline, immediately pre-exercise, immediately post-exercise, immediately pre-lunch, and immediately post-lunch

Study Arms (2)

high-intensity

EXPERIMENTAL

Other: Exercise

low-intensity

EXPERIMENTAL

Other: Exercise

Interventions

Exercise OTHER

high intensity exercise = 15 x 60 s sprints at 85% velocity of VO2max (vVO2max) with 60 s walking at 20% vVO2max or moderate intensity exercise = walking at 60% vVO2max

high-intensity; low-intensity

Eligibility Criteria

• Age: 18 Years - 45 Years
• Gender Eligibility Details: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Female
• Adult
• apparently healthy
• overweight or class I obese
• eumenorrheic

You may not qualify if:

• Diabetes
• pregnancy
• cardiovascular disease
• greater than 1 hour of structured physical activity per week
• thyroid disease
• polycystic ovary disease

Sponsors & Collaborators

• Ohio University: lead
• Marywood University: collaborator

Study Sites (1)

Human Physiology Lab

Scranton, Pennsylvania, 18509, United States

Location

MeSH Terms

Conditions

Overweight; Obesity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: June 15, 2020
• First Posted: June 18, 2020
• Study Start: January 1, 2016
• Primary Completion: June 1, 2016
• Study Completion: August 1, 2016
• Last Updated: June 18, 2020

Record last verified: 2020-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)