NCT06082310

Brief Summary

The management of obesity involves hygienic and dietary measures that include appropriate nutrition and an increase in physical activity (PA). Among the various PA modalities that can be recommended, High-Intensity Interval Training (HIIT) is now recognized as a fun and effective program for promoting fat loss. A meta-analysis conducted by our team suggests a potential influence of the mode of HIIT practice (cycling vs. running) on fat mass (FM) loss. In order to better understand the metabolic adaptations following this type of practice, the investigators propose to compare two isoenergetic HIIT sessions (cycling vs. running) in overweight or obese subjects. The objective is to compare post-recovery (+2h) oxygen consumption, substrate utilization, concurrent energy expenditure and post 24h energy intakes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 11, 2023

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

October 3, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

October 13, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 8, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 8, 2023

Completed
Last Updated

December 11, 2023

Status Verified

December 1, 2023

Enrollment Period

11 months

First QC Date

October 3, 2023

Last Update Submit

December 8, 2023

Conditions

Overweight and Obesity

Keywords

ModalitiesHigh-intensity interval exerciseSubstrate oxidationAppetiteEnergy IntakesEnjoyment

Outcome Measures

Primary Outcomes (1)

  • oxygen consumption during the recovery period

    Determination of oxygen consumption 2 hours after the exercise session (cycling and running). Determination from Metamax (3D Cortex).

    Two hours after the end of the exercise

Secondary Outcomes (2)

  • Lipid and carbohydrate oxidation during and after the exercise session (cycling and running).

    Measurement during exercise and two hours after the end of the exercise

  • Energy intakes 24 hours after the exercise

    24 hours post exercise

Study Arms (2)

High Intensity Interval Training - Biking (HIITBIKE)

EXPERIMENTAL

Cycling exercise: 5 min warm-up + 9-12 x \[45 seconds at 80% of HRmax followed by 1 minute 30 seconds of active recovery at a power equivalent to 40% of HRmax\].

Other: Exercise

High Intensity Interval Training - Running (HIITRUN)

EXPERIMENTAL

Running exercise: 5 min warm-up + 9-12 x \[45 seconds at 80% of HRmax followed by 1 minute 30 seconds of active recovery at a treadmill speed equivalent to 40% of HRmax\].

Other: Exercise

Interventions

ExerciseOTHER

Two HIIT modalities

High Intensity Interval Training - Biking (HIITBIKE)High Intensity Interval Training - Running (HIITRUN)

Eligibility Criteria

Age18 Years - 65 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \- men with overweight or obesity (BMI between 25 kg/m2 and 35 kg/m2)

You may not qualify if:

  • medical contraindications to intense physical activity,
  • painful joints,
  • taking ß-blocker

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CREPS Auvergne Rhône-Alpes / Vichy

Bellerive-sur-Allier, Allier, 03321, France

Location

MeSH Terms

Conditions

OverweightObesity

Interventions

Exercise

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Claire Morel, Dr

    CREPS Auvergne Rhône-Alpes / Vichy

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Data collected on the volunteers will be made anonymous.
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 3, 2023

First Posted

October 13, 2023

Study Start

January 11, 2023

Primary Completion

December 8, 2023

Study Completion

December 8, 2023

Last Updated

December 11, 2023

Record last verified: 2023-12

Locations

FR(1)