NCT04424849

Brief Summary

The most common thorax Computed tomography (CT) findings are multifocal ground-glass opacities and peripheral consolidation in patients with COVID-19. Septal thickening, bronchiectasis, pleural thickening, and subpleural involvement may also be observed. Although these findings are not specific to COVID-19, the severity of pulmonary involvement is expected to be correlated with thorax CT findings.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Mar 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 15, 2020

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 8, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 11, 2020

Completed
4 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2020

Completed
Last Updated

June 11, 2020

Status Verified

June 1, 2020

Enrollment Period

3 months

First QC Date

June 8, 2020

Last Update Submit

June 8, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Invasive respiratory support in patients with COVID-19

    Whether Thorax CT findings predict invasive mechanical ventilation requirement of covid-19 patients

    120 days

Secondary Outcomes (1)

  • Mortality in patients with COVID-19

    120 days

Study Arms (1)

COVID-19 patients

Patient tested positive for COVID-19 who had a CT scan

Diagnostic Test: CT-Scan

Interventions

CT-ScanDIAGNOSTIC_TEST

Chest CT scan on admission to the intensive care unit

COVID-19 patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patient admitted to the intensive care unit with COVID-19 pneumonia confirmed by RT-PCR

You may qualify if:

  • Age ≥ 18 years
  • COVID-19 confirmed by positive RT-PCR and/or antibody testing
  • CT scan at intensive care unit admission

You may not qualify if:

  • Loss of CT data
  • Chronic lung disease findings by CT that may lead to misinterpretation
  • RT-PCR results unavailable or negative
  • Terminal cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tepecik Training and Research Hospital

Izmir, Izmir, Konak, 35170, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

COVID-19

Interventions

Tomography, X-Ray Computed

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Image Interpretation, Computer-AssistedDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisRadiographic Image EnhancementImage EnhancementPhotographyRadiographyTomography, X-RayTomography

Central Study Contacts

Işıl K Güldoğan

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

June 8, 2020

First Posted

June 11, 2020

Study Start

March 15, 2020

Primary Completion

June 15, 2020

Study Completion

July 15, 2020

Last Updated

June 11, 2020

Record last verified: 2020-06

Data Sharing

IPD Sharing
Will not share

Locations