Pulmonary Rehabilitation in Post-Acute Period of COVID-19 Infection

NCT04365738 | Completed DMC

• 1 other identifier: PR COVID-19
• Study Type: interventional
• Target: 270
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the efficacy of pulmonary rehabilitation(PR) applied in the isolation processes of post-acute patients with mild and moderate symptoms who had positive COVID-19 test on dyspnea,muscle pain,chest expansion,lower limb muscle strength and dynamic balance,fatigue,anxiety and depression.

Conditions

COVID-19

Keywords

Pulmonary Rehabilitation; Dyspnea; Fatigue; Pain; Anxiety

Outcome Measures

Primary Outcomes (1)

• Dyspnea

  The Borg scale is a scale scored between 0-10, indicating the severity of dyspnea. 0 indicates no shortness of breath, 10 indicates severe shortness of breath

  Baseline, up to 4 weeks

Secondary Outcomes (4)

• Chest expansion

  Baseline, up to 4 weeks

• Fatigue severity

  Baseline, up to 4 weeks

• Visual Analog Scale for pain

  Baseline, up to 4 weeks

• Hospital anxiety and depression scale

  Baseline, up to 4 weeks

Study Arms (2)

Pulmonary Rehabilitation

EXPERIMENTAL

The patients who applied pulmonary rehabilitation were checked, motivated and followed-up regularly with video calls every day. Pulmonary rehabilitation program consists of patient education, breathing, in-house mobilization and range of motion exercises.

Other: Rehabilitation

Control

PLACEBO COMPARATOR

As a patient education, information was given about the disease and treatment process, listening to the patient during this process and getting regular sleep, balanced nutrition and taking a break from smokers.

Other: Rehabilitation

Interventions

Rehabilitation OTHER

Chest and diaphragm respiration, in-house mobilization, joint range of motion exercises was performed to the patients as breathing exercises.

Control; Pulmonary Rehabilitation

Eligibility Criteria

• Age: 28 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Between the ages of 28-45, positive COVID-19 test, being in the post-acute period, having symptoms of mild-moderate severity, respiratory rate ≤40 breaths / min, patients who can make video speech

You may not qualify if:

• Severe symptom involvement, fever more than 38 degrees, obese patients, patients with multiple comorbidities, patients with one or more organ failure, oxygen saturation in the blood ≤95%, a resting blood pressure of \<90/60 mmHg or\> 140 / 90 mmHg patients

Sponsors & Collaborators

• Istanbul Bilgi University: lead

Study Sites (1)

Istanbul Bilgi University

Istanbul, 34440, Turkey (Türkiye)

Location

MeSH Terms

Conditions

COVID-19; Dyspnea; Fatigue; Pain; Anxiety Disorders

Interventions

Rehabilitation

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurologic Manifestations; Mental Disorders

Intervention Hierarchy (Ancestors)

Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Study Officials

• Tomri̇s Duymaz

  Istanbul Bilgi University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc.Prof.

Study Record Dates

• First Submitted: April 26, 2020
• First Posted: April 28, 2020
• Study Start: March 11, 2020
• Primary Completion: April 10, 2020
• Study Completion: April 26, 2020
• Last Updated: April 28, 2020

Record last verified: 2020-04

Locations

TU (1)