Relaxation Exercise in Patients With COVID-19

NCT04998708 | Completed

• 1 other identifier: 333
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

the aim of this study is to investigate the effect of relaxation techniques on immune biomarkers and disease severity and progression in patients with COVID-19 and the period to which these changes last.

Conditions

Covid19

Outcome Measures

Primary Outcomes (2)

• Immune biomarkers

  5 months

• Wisconsin Upper Respiratory Symptom Survey

  5 months

Study Arms (2)

Intervention

EXPERIMENTAL

The intervention group performed two types of relaxation techniques, that have shown their positive effects on immune functions, including progressive muscle relaxation exercise (PMRs)16 and cognitive-behavioral stress management (CBSM). We used two types of relaxation techniques to produce maximum effects of relaxation techniques within the limited period of COVID-19 quarantine (2 weeks). the control groups did not receive any treatment during the study; however, they were treated afterwards.

Other: Relaxation technique

Control

NO INTERVENTION

Interventions

Relaxation technique OTHER

The intervention group performed two types of relaxation techniques, that have shown their positive effects on immune functions, including progressive muscle relaxation exercise (PMRs)16 and cognitive-behavioral stress management (CBSM)32. We used two types of relaxation techniques to produce maximum effects of relaxation techniques within the limited period of COVID-19 quarantine (2 weeks). the control groups did not receive any treatment during the study; however, they were treated afterwards.

Intervention

Eligibility Criteria

• Age: 25 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• A recent mild or moderate COVID-19 with no or low-grade fever 99.5- 100.94 °F (37.5-38.3 °C)

You may not qualify if:

• Any patient was not hospitalized and had high-grade fever \<100.94 °F (\<38.3 °C) or other chronic diseases such as heart problems, hypertension, or diabetes. Women how were using contraceptives were excluded because contraceptives decrease immune functions and might affect the subjectivity to autoimmune disorders with marked increases in risk for various autoimmune disorders

Sponsors & Collaborators

• Beni-Suef University: lead

Study Sites (1)

Istanbul Gelisim University

Istanbul, Turkey (Türkiye)

Location

Related Publications (1)

• Alawna M, Mohamed AA. An integrated intervention combining cognitive-behavioural stress management and progressive muscle relaxation improves immune biomarkers and reduces COVID-19 severity and progression in patients with COVID-19: A randomized control trial. Stress Health. 2022 Dec;38(5):978-988. doi: 10.1002/smi.3151. Epub 2022 Apr 20.

  PMID: 35393715 DERIVED

MeSH Terms

Conditions

COVID-19

Interventions

Relaxation Therapy

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: August 8, 2021
• First Posted: August 10, 2021
• Study Start: December 1, 2020
• Primary Completion: April 30, 2021
• Study Completion: April 30, 2021
• Last Updated: March 21, 2022

Record last verified: 2021-08

Locations

TU (1)