NCT04423315

Brief Summary

Covid-19 mainly affects the respiratory system. Multiple organ dysfunction and a particularly progressive respiratory insufficiency along with a widespread coagulopathy presumed to be due to infection-associated inflammation and the resulting cytokine storm, are strongly associated with high mortality rates. In this study, the association between thrombosis risk and clinical presentation of Covid-19 is investigated.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 5, 2020

Completed
3 days until next milestone

Study Start

First participant enrolled

June 8, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 9, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 15, 2020

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2020

Completed
Last Updated

September 23, 2020

Status Verified

September 1, 2020

Enrollment Period

1 month

First QC Date

June 5, 2020

Last Update Submit

September 21, 2020

Conditions

Keywords

covid-19 pneumoniathromboembolism risklength of hospitalization

Outcome Measures

Primary Outcomes (1)

  • length of hospital stay

    from admission to discharge expressed in days

    2 months

Study Arms (1)

patients with covid-19 pneumonia

patients with covid-19 pneumonia above 18 years old who were diagnosed by pcr testing and computed tomography of thorax

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with COVID - 19 pneumonia diagnosed in the emergency, internal medicine and cardiology outpatient clinics will be included

You may qualify if:

  • patients diagnosed with COVID - 19 pneumonia between March 11 th , 2020 and April 25th, 2020 in the emergency, internal medicine and cardiology outpatient clinics.
  • patients diagnosed by pcr testing and computed tomography of the chest

You may not qualify if:

  • patients below 18 years of age
  • patients with an alternative aetiology of pneumonia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Vital Hospital

Bahçelievler, Istanbul, 34230, Turkey (Türkiye)

Location

Related Publications (2)

  • Wang Q, Ma J, Jiang Z, Ming L. Prognostic value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in acute pulmonary embolism: a systematic review and meta-analysis. Int Angiol. 2018 Feb;37(1):4-11. doi: 10.23736/S0392-9590.17.03848-2. Epub 2017 May 24.

    PMID: 28541022BACKGROUND
  • Lippi G, Plebani M. Laboratory abnormalities in patients with COVID-2019 infection. Clin Chem Lab Med. 2020 Jun 25;58(7):1131-1134. doi: 10.1515/cclm-2020-0198. No abstract available.

    PMID: 32119647BACKGROUND

MeSH Terms

Conditions

Coronavirus InfectionsThromboembolism

Condition Hierarchy (Ancestors)

Coronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsVirus DiseasesInfectionsEmbolism and ThrombosisVascular DiseasesCardiovascular Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D.

Study Record Dates

First Submitted

June 5, 2020

First Posted

June 9, 2020

Study Start

June 8, 2020

Primary Completion

July 15, 2020

Study Completion

July 20, 2020

Last Updated

September 23, 2020

Record last verified: 2020-09

Locations