Persistence of Symptoms After Improvement of Acute COVID-19

NCT04764773 | Completed

• 1 other identifier: Soh-Med-21-02-46
• Study Type: observational
• Target: 172
• Locations: 1 country
• Sites: 1

Brief Summary

Coronavirus disease pandemic has been started in late 2019. Survivors of COVID-19 are significantly more likely to develop clinical sequelae three months after discharge from the hospital than those without COVID-19 infection. This is true not only for general and respiratory symptoms but also for cardiovascular and psychosocial symptoms. This suggests that these symptoms may indeed be the sequelae of recovery for COVID-19 survivors. So, we aimed to detect the prevalence and to evaluate the type of symptoms that could persist after the recovery from COVID19 infection in Sohag governorate, Egypt.

Conditions

Corona Virus Infection

Keywords

Persistent symptoms; Recovery; COVID-19

Outcome Measures

Primary Outcomes (3)

• Percentage of patient who had persistent symptoms after recovery of acute covid19

  during the period from 15th May,2020 to the end of February, 2021

• Type of persistent symptom after acute covid19

  during the period from the start of June 2020 to the end of July 2020

• Risk factors for persistent symptoms after recovery of acute covid19

  during the period from 15th May,2020 to the end of February, 2021

Study Arms (2)

Case

Patient who had COVID19 infection

Other: No intervention

control

healthy volunteer who were age and sex matched with our patients

Other: No intervention

Interventions

No intervention OTHER

No intervention

Case; control

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients who were test positive for SARS-CoV2 and were improved and discharged from Sohag isolation hospitals and isolation department for COVID19 in Sohag University hospitals

You may qualify if:

• Positive for SARS-CoV2

You may not qualify if:

• Patients with severe complex illness, pregnant or lactating females and patient who refuse to participate or give complete detailed history

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Mona Mohammed Abdelrahman

Sohag, Egypt

Location

Related Publications (2)

• Xiong Q, Xu M, Li J, Liu Y, Zhang J, Xu Y, Dong W. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Clin Microbiol Infect. 2021 Jan;27(1):89-95. doi: 10.1016/j.cmi.2020.09.023. Epub 2020 Sep 23.

  PMID: 32979574 BACKGROUND

• Abdelrahman MM, Abd-Elrahman NM, Bakheet TM. Persistence of symptoms after improvement of acute COVID19 infection, a longitudinal study. J Med Virol. 2021 Oct;93(10):5942-5946. doi: 10.1002/jmv.27156. Epub 2021 Jul 2.

  PMID: 34171139 DERIVED

MeSH Terms

Conditions

Coronavirus Infections; COVID-19

Condition Hierarchy (Ancestors)

Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Virus Diseases; Infections; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Noha Abdelrahman, assistant-lecturer

  Sohag University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: February 19, 2021
• First Posted: February 21, 2021
• Study Start: May 1, 2020
• Primary Completion: February 28, 2021
• Study Completion: March 31, 2021
• Last Updated: November 2, 2021

Record last verified: 2021-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)