NCT04419116

Brief Summary

The mobile bearing unicompartmental knee arthroplasty has shown excellent clinical outcome and survivorship. However, some studies have shown that the patients still had medial knee pain and shown worst the clinical outcome, even though the survivorship was excellent. The medial knee pain after operation was the one cause of revision. The incidence of medial knee pain was 0%-9%. The cause of medial knee pain was overloading on the medial plateau, local inflammation, over hanging of the tibial component and overstretching of the MCL due to the application of excessive polyethylene. Therefore, the tibia in this study was cut with under resection technique for reducing the overloading on the medial tibial plateau. The purpose of this study is to compare medial knee pain between tibial bone cut preservation technique and conventional tibial bone cut technique following mobile bearing UKA.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P75+ for not_applicable knee-osteoarthritis

Timeline
Completed

Started Jun 2018

Longer than P75 for not_applicable knee-osteoarthritis

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2018

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

June 1, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 5, 2020

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2021

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2022

Completed
Last Updated

August 31, 2021

Status Verified

August 1, 2021

Enrollment Period

3.2 years

First QC Date

June 1, 2020

Last Update Submit

August 29, 2021

Conditions

Keywords

mobile bearing UKAOxford UKAmedial knee pain

Outcome Measures

Primary Outcomes (1)

  • visual analog scale (VAS) for pain

    pain at medial tibial plateau

    2 years

Secondary Outcomes (5)

  • knee society score

    2 years

  • Oxford knee score

    2 years

  • joint forgotten score

    2 years

  • knee injury osteoarthritis outcome score

    2 years

  • Kujala score

    2 years

Study Arms (2)

tibial preservation bone cut

EXPERIMENTAL

tibial preservation bone cut following mobile bearing UKA

Procedure: tibial preservation bone cut

tibial conventional bone cut

EXPERIMENTAL

tibial conventional bone cut following mobilebearing UKA

Procedure: tibial preservation bone cut

Interventions

tibial preservation bone cut: removing of proximal tibial less than conventional tibial bone cut with 2mm.

tibial conventional bone cuttibial preservation bone cut

Eligibility Criteria

Age50 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • medial osteoarthritis of knee

You may not qualify if:

  • posttraumatic arthritis
  • gout
  • Rheumatoid arthritis
  • anterior cruciate ligament insufficiency
  • osteonecrosis of knee

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Boonchana Pongcharoen

Pathum Thani, 12120, Thailand

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • Boonchana Pongcharoen

    faculty of medicine, Thammasat university

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associated professor

Study Record Dates

First Submitted

June 1, 2020

First Posted

June 5, 2020

Study Start

June 1, 2018

Primary Completion

August 1, 2021

Study Completion

November 1, 2022

Last Updated

August 31, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will not share

Locations