Serum Vitamin D Levels and Pregnancy Rates in Women Undergoing Elective Frozen Embryo Transfer (eFET)
Comparing the Serum Vitamin D Levels and Pregnancy Rates in Women Undergoing Elective Frozen Embryo Transfer (eFET)
1 other identifier
observational
200
1 country
1
Brief Summary
The aim of this study is determining the affects of serum vitamin D levels to implantation and clinical pregnancy rates in women undergoing elective vitrified/thawed embryo transfer. Two groups will be identified according to the serum vitamin D levels on eFET transfer day and later on implantation, clinical pregnancy and ongoing pregnancy rates will be compared between those groups
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2015
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 8, 2015
CompletedFirst Posted
Study publicly available on registry
February 12, 2015
CompletedStudy Start
First participant enrolled
April 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2016
CompletedJanuary 28, 2016
January 1, 2016
1.2 years
February 8, 2015
January 27, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
clinical pregnancy rate
The presence of intrauterine gestational sac at 7 weeks of gestation
4 weeks after embryo transfer
Secondary Outcomes (2)
implantation rates
3 weeks after embryo transfer
ongoing pregnancy rates
18 weeks after embryo transfer
Study Arms (2)
vitamin D deficient patients
Serum 25- (hydroxide) OH Vitamin D levels \<20ng/L undergoing Frozen embryo transfer (Vitamin D levels are measured on the day of embryo transfer)
vitamin D sufficient patients
Serum 25- (hydroxide) OH Vitamin D levels \>20ng/L undergoing Frozen embryo transfer (Vitamin D levels are measured on the day of embryo transfer)
Interventions
comparison of groups according to their serum vitamin D levels on frozen embryo transfer day
Eligibility Criteria
Infertile women undergoing a frozen ET with 1 Day 5 (blastocyst stage) embryo
You may qualify if:
- years to 35 years age, a frozen ET with 1 Day 5 (blastocyst stage) embryo
- Infertile women undergoing ICSI (intracytoplasmic sperm injection) cycle
- Factors affecting fertility are Tubal
- Unexplained or ovulatory disturbances,
You may not qualify if:
- Need to do Preimplantation Genetic Diagnosis
- Presence of endometriosis and adenomyosis
- Severe male factor infertility
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Bahceci Cliniclead
Study Sites (1)
Bahceci Fulya IVF Center
Istanbul, Fulya, 34800, Turkey (Türkiye)
Related Publications (1)
Rudick B, Ingles S, Chung K, Stanczyk F, Paulson R, Bendikson K. Characterizing the influence of vitamin D levels on IVF outcomes. Hum Reprod. 2012 Nov;27(11):3321-7. doi: 10.1093/humrep/des280. Epub 2012 Aug 21.
PMID: 22914766BACKGROUND
Study Officials
- STUDY DIRECTOR
mustafa bahceci
bahceci Fulya IVF center
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
February 8, 2015
First Posted
February 12, 2015
Study Start
April 1, 2015
Primary Completion
June 1, 2016
Study Completion
July 1, 2016
Last Updated
January 28, 2016
Record last verified: 2016-01