NCT04399304

Brief Summary

In this study, bilateral simultaneous high tibial osteotomy (HTO) was compared with staged bilateral HTO in terms of complications. We did not use any grafts to support the osteotomy line and the patients were mobilized immediately with a full load on a postoperative day 1. And our hypothesis is that bilateral simultaneous applications are safe in comparison to the staged ones in terms of complications.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 19, 2014

Completed
5.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 19, 2019

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 19, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 19, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 22, 2020

Completed
Last Updated

May 22, 2020

Status Verified

May 1, 2020

Enrollment Period

5.1 years

First QC Date

May 19, 2020

Last Update Submit

May 19, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Complications

    Total complications rate

    2 year

Secondary Outcomes (1)

  • Radiologic assesment

    2 year

Study Arms (2)

Simultaneous

One-stage bilateral high tibial osteotomy

Procedure: simultaneous bilateral high tibial osteotomy

Staged

Two-stage bilateral high tibial osteotomy

Procedure: Staged bilateral high tibial osteotomy

Interventions

One-stage simultaneous bilateral high tibial osteotomy

Simultaneous

Two-stage bilateral high tibial osteotomy

Staged

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with bilateral genu varus gonarthrosis operated by the tertiary step hospital high-volume knee surgeons

You may qualify if:

  • Bilateral primary genu varus gonarthrosis

You may not qualify if:

  • Secondary gonarthrosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bezmialem Vakif University

Istanbul, Fatih, 34000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, Resident Doctor in Orthopaedic Surgery

Study Record Dates

First Submitted

May 19, 2020

First Posted

May 22, 2020

Study Start

November 19, 2014

Primary Completion

December 19, 2019

Study Completion

May 19, 2020

Last Updated

May 22, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will not share

Locations