NCT04394039

Brief Summary

In this study it is aimed to investigate the difference between the brain response to different urban environments in Singapore before and after the COVID-19 pandemic. The datasets acquired from 34 healthy individuals as part of ongoing study "Effects of Landscape on the Brain" (IRB Ref #: S-18-352) will be used. These datasets consist of neurophysiological data recordings and behavioral self-reported measures and were collected before 20 of January 2020. The same experimental protocol would be followed, given that the data collection in the lab-setting would start after 7 th May 2020/whenever research activities are allowed to resume, and the outdoor sessions after the "circuit-breaker" period in Singapore is over.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 13, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 19, 2020

Completed
13 days until next milestone

Study Start

First participant enrolled

June 1, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2020

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

July 15, 2021

Status Verified

July 1, 2021

Enrollment Period

2 months

First QC Date

May 13, 2020

Last Update Submit

July 9, 2021

Conditions

Keywords

landscapeexposureEEGfNIRSstressurbanself-isolationcovid-19pandemicpublic spacebrain

Outcome Measures

Primary Outcomes (3)

  • EEG power in alpha band

    predictor of positive affect and positive mental health outcomes, measured with EEG

    5 minutes

  • EEG power in beta band

    more beta in the right temporal lobes associated with stimuli-driven attention, measured with EEG

    5 minutes

  • fNIRS haemodynamics

    decreased oxy-hemoglobin in the frontal part of the brain indicates more relaxation

    5 minutes

Secondary Outcomes (2)

  • Profile of mood states

    30 minutes

  • landscape preference measured with self-assessment manikin scale

    30 minutes

Study Arms (1)

public sp exposures

EXPERIMENTAL

All participants undergo the procedure of visiting all landscape exposures in a random order.

Other: Public space exposure

Interventions

landscapes with nature and/or classified as contemplative (through a CLM psychometric measure) are expected to elicit different brainwave oscillations as compared to noncontemplative ones.

public sp exposures

Eligibility Criteria

Age21 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age of 21 to 75
  • Right-handed only

You may not qualify if:

  • left-handed
  • serious visual or auditory impairment
  • Major neurological disorders e.g. epilepsy, stroke
  • Any form of cancer
  • Major heart diseases: e.g. ischemic heart disease
  • Major lung diseases: e.g. chronic obstructive pulmonary disorder.
  • Major liver disease e.g. liver failure
  • Major kidney disease e.g. kidney failure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute for Health Innovation & Technology (iHealthtech)

Singapore, 117599, Singapore

Location

MeSH Terms

Conditions

Anxiety DisordersCOVID-19

Condition Hierarchy (Ancestors)

Mental DisordersPneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Masking Details
participants do not know the hypothesis of the study, other people cannot influence the brainwave reaction
Purpose
SUPPORTIVE CARE
Intervention Model
SEQUENTIAL
Model Details: within-subjects before/ after study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

May 13, 2020

First Posted

May 19, 2020

Study Start

June 1, 2020

Primary Completion

August 1, 2020

Study Completion

December 31, 2020

Last Updated

July 15, 2021

Record last verified: 2021-07

Data Sharing

IPD Sharing
Will not share

Locations