NCT04387552

Brief Summary

This study aims to improve adherence to American Academy of Pediatrics safe sleep (SS) recommendations and improve rates of initiation and duration of partial and exclusive breastfeeding (BF) through direct education of mothers using Mobile Health (mHealth) technologies (ex. text messaging).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,126

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 10, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 14, 2020

Completed
1.7 years until next milestone

Study Start

First participant enrolled

January 20, 2022

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 7, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 7, 2025

Completed
Last Updated

April 17, 2026

Status Verified

April 1, 2026

Enrollment Period

3.4 years

First QC Date

May 10, 2020

Last Update Submit

April 14, 2026

Conditions

Keywords

Breastfeeding (BF)Sleep positionSafe Sleep (SS)Mobile MessagingSocial MediaWIC

Outcome Measures

Primary Outcomes (5)

  • Infant sleep position in the previous two weeks

    An investigator-developed maternal survey will be used to assess infant's sleep position during the previous two weeks with categorical responses of back, stomach, side, and other. We will examine: A) Usual position; B) Exclusive use of supine position

    Between 2 and 6 months

  • Infant sleep location in the previous two weeks

    An investigator-developed maternal survey will be used to assess the infant's sleep location during the previous two weeks with categorical responses of room sharing without bed sharing, room sharing with bed sharing, no room sharing and no bed sharing. We will examine: A) Usual location; B) Exclusive location of room sharing without bedsharing

    Between 2 and 6 months

  • Any Soft bedding use in the previous two weeks

    An investigator-developed maternal survey will be used to assess soft bedding placed in and around the infant (while sleeping) during the previous two weeks with categorical responses of Yes or No.

    Between 2 and 6 months

  • Any Pacifier use in the previous two weeks

    An investigator-developed maternal survey will be used to assess the infant's pacifier use during the previous two weeks with categorical responses of Yes or No.

    Between 2 and 6 months

  • Infant feeding in the previous two weeks

    An investigator-developed maternal survey will be used to assess whether the infant was breast fed during the previous two weeks with categorical responses of exclusively breast fed, partially breast fed, or not breast fed. We will examine: A) Any breast milk feeding; B) Exclusive breast milk feeding

    Between 2 and 6 months

Secondary Outcomes (10)

  • Any Initiation of breast milk feeding

    Between 36 weeks gestational age and birth

  • Planned infant sleep position after birth of baby

    Between 36 weeks gestational age and birth.

  • Planned infant sleep location after birth of baby

    Between 36 weeks gestational age and birth.

  • Planned breast milk feeding after birth of baby

    Between 36 weeks gestational age and birth.

  • Planned duration of breast milk feeding after birth of baby

    Between 36 weeks gestational age and birth

  • +5 more secondary outcomes

Study Arms (4)

Prenatal SS/Postnatal BF

EXPERIMENTAL

Prenatal Safe Sleep/Postnatal Breastfeeding Mobile Health Messages

Behavioral: Prenatal Safe Sleep Mobile Health (mHealth) MessagingBehavioral: Postnatal Breastfeeding Mobile Health (mHealth) Messaging

Prenatal BF/Postnatal SS

EXPERIMENTAL

Prenatal Breastfeeding/Postnatal Safe Sleep Mobile Health Messages

Behavioral: Prenatal Breastfeeding Mobile Health (mHealth) MessagingBehavioral: Postnatal Safe Sleep Mobile Health (mHealth) Messaging

Prenatal SS/Postnatal SS

EXPERIMENTAL

Prenatal Safe Sleep/Postnatal Safe Sleep Mobile Health Messages

Behavioral: Prenatal Safe Sleep Mobile Health (mHealth) MessagingBehavioral: Postnatal Safe Sleep Mobile Health (mHealth) Messaging

Prenatal BF/Postnatal BF

EXPERIMENTAL

Prenatal Breastfeeding/Postnatal Breastfeeding Mobile Health Messages

Behavioral: Prenatal Breastfeeding Mobile Health (mHealth) MessagingBehavioral: Postnatal Breastfeeding Mobile Health (mHealth) Messaging

Interventions

Participants will receive prenatal Safe Sleep mHealth messaging starting at 34 weeks gestation until birth of their baby.

Prenatal SS/Postnatal BFPrenatal SS/Postnatal SS

Participants will receive prenatal Breastfeeding mHealth messaging starting at 34 weeks gestation until birth of their baby.

Prenatal BF/Postnatal BFPrenatal BF/Postnatal SS

Upon birth of baby, participants will begin receiving postnatal Safe Sleep mHealth messaging for a two month period.

Prenatal BF/Postnatal SSPrenatal SS/Postnatal SS

Upon birth of baby, participants will begin receiving postnatal Breastfeeding mHealth messaging for a two month period.

Prenatal BF/Postnatal BFPrenatal SS/Postnatal BF

Eligibility Criteria

Age14 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Must be client at a WIC center participating in study.
  • Must be pregnant and less than 34 weeks gestation
  • Must speak English or Spanish
  • Must live in the United States
  • Must have texting capabilities via mobile phone
  • Must plan to live in same household as infant after birth.

You may not qualify if:

  • A prenatal diagnosis expected to have impact on infant care practices not compatible with study goals, including contraindications to breastfeeding or supine infant sleep positioning.
  • Meets the definition of a minor according to applicable state law.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Boston University Medical Campus

Boston, Massachusetts, 02118, United States

Location

MeSH Terms

Conditions

Breast FeedingSudden Infant Death

Interventions

Telemedicine

Condition Hierarchy (Ancestors)

Feeding BehaviorBehaviorDeath, SuddenDeathPathologic ProcessesPathological Conditions, Signs and SymptomsInfant Death

Intervention Hierarchy (Ancestors)

Delivery of Health CarePatient Care ManagementHealth Services Administration

Study Officials

  • Michael J Corwin, MD

    Boston University School of Public Health, Dept of Pediatrics, BUSM

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 10, 2020

First Posted

May 14, 2020

Study Start

January 20, 2022

Primary Completion

June 7, 2025

Study Completion

June 7, 2025

Last Updated

April 17, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations