NCT04385212

Brief Summary

In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly understood in older patients and is certainly different from the general population. This project is designed to better understand and to determine clinical, biological and radiological markers of poor adverse outcomes in hospitalized older patients diagnosed with COVID-19.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
230

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 13, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 14, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 14, 2020

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

April 29, 2020

Completed
13 days until next milestone

First Posted

Study publicly available on registry

May 12, 2020

Completed
Last Updated

May 12, 2020

Status Verified

May 1, 2020

Enrollment Period

1 month

First QC Date

April 29, 2020

Last Update Submit

May 8, 2020

Conditions

Coronavirus InfectionSars-CoV2Elderly InfectionOld Age; Debility

Outcome Measures

Primary Outcomes (1)

  • To evaluate the relative contributions of comorbidities on intra-hospitalized death

    We measure functional score of comorbidities

    1 month

Secondary Outcomes (2)

  • To evaluate the relative contributions of functional characteristics on intra-hospitalized death

    1 month

  • To explore specific clinical profiles that may influence COVID-19 disease outcomes in the elderly based on geriatrics syndromes

    1 month

Eligibility Criteria

Age65 Years+
Sexall
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All the patients hospitalized in our geriatrics department with Sars-Cov-2 infection

You may qualify if:

  • Diagnosis of COVID-19, defined by a positive polymerase chain reaction (PCR) test for SARS-CoV-2 detection, obtained by a nasopharyngeal swab or sputum sample.
  • Or patients with negative virus detection in the PCR test, but with a high clinical suspicion will also be considered with COVID-19.

You may not qualify if:

  • \- Presence of document indicating a refusal to participate in a research study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Rehabilitation and Geriatrics

Geneva, 1256, Switzerland

Location

MeSH Terms

Conditions

Coronavirus InfectionsFrailty

Condition Hierarchy (Ancestors)

Coronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsVirus DiseasesInfectionsPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 29, 2020

First Posted

May 12, 2020

Study Start

March 13, 2020

Primary Completion

April 14, 2020

Study Completion

April 14, 2020

Last Updated

May 12, 2020

Record last verified: 2020-05

Locations

CH(1)