SARS-CoV-2 /COVID-19 Admission Screening in a University Hospital Setting

NCT04519372 | Completed

• 1 other identifier: 2020-00808
• Study Type: observational
• Target: 4,099
• Locations: 1 country
• Sites: 1

Brief Summary

The proportion of asymptomatic carriers of SARS-CoV-2 remains elusive, so the potential benefit of systematic screening during the SARS-CoV-2-pandemic is controversial. We investigate the proportion of asymptomatic inpatients who were identified by systematic screening for SARS-CoV-2 upon hospital admission. Adult patients admitted to the University Hospital Basel from 01.04.-14.06.2020 were routinely tested for SARS-CoV-2 within 72 hours of admission by nasopharyngeal swabs. Each patient screened during the study period was retrospectively classified symptomatic or asymptomatic for COVID-19 based on medical chart review.

Conditions

Covid19; SARS-CoV-2

Keywords

Screening; asymptomatic

Outcome Measures

Primary Outcomes (1)

• Proportion of SARS-CoV-2 -infected patients

  We aim to determine the proportion of SARS-CoV-2-infected patients detected by systematic at-admission screening

  01.04.2020-14.06.2020

Interventions

Testing for SARS-CoV-2 DIAGNOSTIC_TEST

All Patients admitted to the hospital were routinely tested for SARS-CoV-2 within 72 hours of admission by nasopharyngeal swabs.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The patient population is defined as all patients with an inhospital casenumber and a screening swab for SARS-CoV-2 at the University Hospital Basel from April 1st, 2020 to June 14th, 2020.

You may qualify if:

• The patient population is defined as all adult patients hospitalized in the University Hospital Basel from April 1st, 2020 to June 14th, 2020.

You may not qualify if:

• Outpatients
• Patients with SARS-CoV-2 screening in the outpatient test center
• Patients with a SARS-CoV-2 test more than 72 hours before hospital admission
• Test not performed (for any reason)

Sponsors & Collaborators

• University Hospital, Basel, Switzerland: lead

Study Sites (1)

University Hospital Basel, Division of Infectious Diseases and Hospital Epidemiology

Basel, 4031, Switzerland

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Sarah Tschudin-Sutter, Prof. Dr. MD

  University Hospital Basel, Division of Infectious Diseases and Hospital Epidemiology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 17, 2020
• First Posted: August 19, 2020
• Study Start: April 1, 2020
• Primary Completion: June 14, 2020
• Study Completion: March 31, 2021
• Last Updated: May 18, 2021

Record last verified: 2021-05

Locations

CH (1)