Assessment of Covid-19 Infection Rates in Healthcare Workers Using a Desynchronization Strategy

NCT04333862 | Completed

• 1 other identifier: 2020-00563
• Study Type: observational
• Target: 519
• Locations: 1 country
• Sites: 1

Brief Summary

Desynchronization of infection rates in healthcare workers will potentially reduce the early infection rates and therefore maintain workforce for late time points of the epidemic. Given the current threat of the COVID-19 epidemic, the department for Visceral Surgery and Medicine, Bern University Hospital, has decided to limit its elective interventions to oncological and life-saving procedures only. At the same time, the medical team were split in two teams, each working for 7 days, followed by 7 days off, called a desynchronization strategy. Contacts between the two teams are avoided. The main aim of present study is to determine, if the infection rate between the two populations (at work versus at home) is different. Secondary aims are to determine if the workforce can be maintained for longer periods compared standard of care, and if the infection rate among patients hospitalized for other reasons varies compared to the community.

Conditions

SARS-CoV-2

Keywords

SARS-CoV-2; COVID-19

Outcome Measures

Primary Outcomes (1)

• Fraction of healthcare workers infected with SARS-CoV-2

  To determine the infection rate of healthcare workers providing healthcare versus those who are staying at home, in a desynchronization work strategy

  90 days

Secondary Outcomes (3)

• Fraction of healthcare workers with COVID-19

  90 days

• Number of patients infected in the hospital

  90 days

• Development of SARS-CoV2 specific antibody repertoire

  18 months

Study Arms (3)

Healthcare workers providing healthcare

To determine the infection rate of healthcare workers providing healthcare versus those who are staying at home, in a desynchronization work strategy

Healthcare workers staying at home

To determine the infection rate of healthcare workers providing healthcare versus those who are staying at home, in a desynchronization work strategy

Hospitalized patients

To compare the infection rate of hospitalized patients versus healthcare workers

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Health care workers and patients of the Department for Visceral Surgery and Medicine

You may qualify if:

• Healthcare workers of the Department for Visceral Surgery and Medicine
• Patients of the Department for Visceral Surgery and Medicine
• Written informed consent

You may not qualify if:

• No informed consent
• Patients with known COVID-19 infection before hospitalization in the investigators' department

Sponsors & Collaborators

• Insel Gruppe AG, University Hospital Bern: lead

Study Sites (1)

Guido Beldi

Bern, Switzerland

Location

Biospecimen

Retention: SAMPLES WITH DNA

Collection of nasal swabs twice per week and blood.

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Guido Beldi, Prof. Dr.

  Insel Gruppe AG, University Hospital Bern

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 1, 2020
• First Posted: April 3, 2020
• Study Start: March 19, 2020
• Primary Completion: March 31, 2023
• Study Completion: March 31, 2023
• Last Updated: November 13, 2024

Record last verified: 2024-11

Locations

CH (1)