Minimal Flow Application in One Lung Ventilation

NCT04376307 | Unknown

• 1 other identifier: 2020/514/172/15
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Interest in low fresh gas flow anesthesia has increased in recent years. The high standard of anesthesia machines, the presence of monitors that continuously and thoroughly analyze the anesthetic gas composition, and the increased knowledge of the pharmacodynamics and pharmacokinetics of inhalation anesthetics greatly facilitated the safe administration of low-flow anesthesia.Low-flow anesthesia can be mentioned for most patients if modern re-breathing systems are used but only if the fresh gas flow rate is reduced below 2 lt / min. In 1974, Virtue was defined as a technique called minimal flow, in which the fresh gas flow was not exceeded 0.5 lt / min. Although there are too many applications for low current in the literature, there is little literature for use in one lung.

Conditions

Ventilator Lung; Anesthesia; Functional

Keywords

one lung ventilation; low flow anesthesia; gas consumption

Outcome Measures

Primary Outcomes (18)

• Age

  Years

  during surgery

• Gender

  Male/Female

  during surgery

• ASA :

  I, II, III, IV

  during surgery

• Height:

  centimeter

  during surgery

• Weight

  kilogram

  during surgery

• BMI:

  kg/m2

  during surgery

• Side of surgery

  left /right

  during surgery

• Side of double lumen tube

  left/right

  during surgery

• Desfluran consumption

  ml

  during surgery

• Heart Rate

  beats /minute

  during surgery

• SpO2

  percent

  during surgery

• Systolic Blood Pressure

  mmHg/min

  during surgery

• Diastolic Blood Pressure

  mmHg/min

  during surgery

• Respiratory Rate

  frequency/ min

  during surgery

• Intubation tube size

  french

  during surgery

• duration of anesthesia

  minutes

  during surgery

• Duration of single lung ventilation

  minutes

  during surgery

• Operation time

  minutes

  during surgery

Study Arms (1)

minimal flow anesthesia

EXPERIMENTAL

the patiennts who have thoracic sugery with one lung ventilaiton

Procedure: minimal flow anesthesia

Interventions

minimal flow anesthesia PROCEDURE

Investigators will use minimal flow anesthesia (0,5 lt/min) during surgery with one lung ventilation

minimal flow anesthesia

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ASA 1-3 Patients
• Single lung ventilation during the operation
• Age\>18

You may not qualify if:

• Age\<18
• ASA 4
• pregnancy
• COPD patients

Sponsors & Collaborators

• Dr. Lutfi Kirdar Kartal Training and Research Hospital: lead

Study Sites (1)

University of Health Sciences Kartal Dr. Lutfi Kirdar Education and Research Hospital

Istanbul, 34860, Turkey (Türkiye)

RECRUITING

Related Publications (2)

• Baum JA. Low-flow anesthesia: theory, practice, technical preconditions, advantages, and foreign gas accumulation. J Anesth. 1999;13(3):166-74. doi: 10.1007/s005400050050. No abstract available.

  PMID: 14530937 BACKGROUND

• Honemann CW, Hahnenkamp K, Mollhoff T, Baum JA. Minimal-flow anaesthesia with controlled ventilation: comparison between laryngeal mask airway and endotracheal tube. Eur J Anaesthesiol. 2001 Jul;18(7):458-66. doi: 10.1046/j.1365-2346.2001.00868.x.

  PMID: 11437874 BACKGROUND

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, Principal Investigator

Model Details: prospectice randomized

Study Record Dates

• First Submitted: April 24, 2020
• First Posted: May 6, 2020
• Study Start: May 5, 2020
• Primary Completion: August 31, 2020
• Study Completion: September 1, 2020
• Last Updated: May 6, 2020

Record last verified: 2020-05

Locations

TU (1)