Prevalence of COVID-19 Infection Among HCW in a French University Hospital

NCT04371692 | Completed

• 2 other identifiers: 2020_352020-A00951-38
• Study Type: observational
• Target: 900
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to determine the prevalence of SARS-Cov2 infection among health care workers exposed of Lille University Hospital, to describe its evolution during the epidemic taking into account the influence of occupational and environmental exposure determinants.

Conditions

Sars-CoV2

Keywords

Prevalence; Health Care Workers; occupational exposure; environmental exposure; serological testing; RT-PCR

Outcome Measures

Primary Outcomes (1)

• the prevalence of SARS- Cov2 infection Health Care Worker with or without symptoms suggestive of a COVID-19 infection

  at 2 months

Secondary Outcomes (5)

• the prevalence of SARS- Cov2 infection Health Care Worker with or without symptoms suggestive of a COVID-19 infection

  once week during 2 months

• Occupational exposures associated with the SARS-Cov2 infection

  once week during 2 months

• Environmental exposures associated with the SARS-Cov2 infection

  once week during 2 months

• immunologic status of health Care Worker

  once week during 2 months

• inflammatory biomarkers status of Health Care Worker

  once week during 2 months

Study Arms (3)

High-risk

staff working in a unit specifically for patients infected or suspected of being infected with SARS-Cov2

Other: self-administered questionnaire; Diagnostic Test: SARS-Cov2 testing

Medium- risk

staff working in a unit that can accommodate patients infected or suspected of being infected with SARS-Cov2, i.e., all care services that do not fall into the high-risk group.

Other: self-administered questionnaire; Diagnostic Test: SARS-Cov2 testing

Low-risk

off-patient staff

Other: self-administered questionnaire; Diagnostic Test: SARS-Cov2 testing

Interventions

self-administered questionnaire OTHER

Every weeks during 2 months, clinical and occupational questionnaire are performed among a cohort of HCW exposed to covid occupational exposure

Also known as: a specifically designed self-administered questionnaire

High-risk; Low-risk; Medium- risk

SARS-Cov2 testing DIAGNOSTIC_TEST

Every weeks during 2 month, SARS-Cov2 RT-PCR, serological testing are performed among a cohort of HCW exposed to covid occupational exposure

High-risk; Low-risk; Medium- risk

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Health Care workers with or without symptoms suggestive of a COVID-19 infection

You may qualify if:

• \- Health Care workers with or without symptoms suggestive of a COVID-19 infection

You may not qualify if:

• HCW working off-site at the CHU de Lille
• HCW on sick leave.
• HCW outside the Lille University Hospital temporarily coming as reinforcements in the context of the epidemic.

Sponsors & Collaborators

• University Hospital, Lille: lead
• Fondation Santé Roquette: collaborator

Study Sites (1)

Hop Claude Huriez Chu Lille

Lille, 59037, France

Location

MeSH Terms

Interventions

COVID-19 Testing

Intervention Hierarchy (Ancestors)

Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques

Study Officials

• Annie SOBASZEK, MD

  University Hospital, Lille

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 28, 2020
• First Posted: May 1, 2020
• Study Start: June 15, 2020
• Primary Completion: July 9, 2020
• Study Completion: July 9, 2020
• Last Updated: April 23, 2021

Record last verified: 2021-04

Locations

FR (1)