NCT04342494

Brief Summary

This research study is being conducted to understand if patients benefit from mobile health interventions while waiting for in-clinic mental health treatments, and to understand which patients receive the most benefit.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,118

participants targeted

Target at P75+ for not_applicable depression

Timeline
Completed

Started May 2020

Typical duration for not_applicable depression

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 8, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 13, 2020

Completed
1 month until next milestone

Study Start

First participant enrolled

May 13, 2020

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 22, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 22, 2023

Completed
2.1 years until next milestone

Results Posted

Study results publicly available

March 17, 2025

Completed
Last Updated

March 17, 2025

Status Verified

February 1, 2025

Enrollment Period

2.8 years

First QC Date

April 8, 2020

Results QC Date

February 27, 2025

Last Update Submit

February 27, 2025

Conditions

Keywords

Behavioral healthPrecision health

Outcome Measures

Primary Outcomes (1)

  • Change in Depression as Measured by the Patient Health Questionnaire 9 (PHQ-9)

    The PHQ-9 was a multipurpose instrument for screening, diagnosing, monitoring and measuring the severity of depression. The PHQ-9 incorporated self-report questions on 9 specific depression symptoms that align with the DSM-IV depression diagnostic criteria. PHQ-9 scores ranged from 0-27, with 0 indicating no depression and 27 indicating severe depression.

    Up to 6 weeks

Secondary Outcomes (5)

  • Mood as Measured by the Mental Health App Assessment

    Daily up to 6 weeks

  • Change in Suicide Risk as Measured by the Positive and Negative Suicide Ideation Inventory - Positive Ideation (PANSI-PI)

    Up to 6 weeks

  • Change in Suicide Risk as Measured by the Positive and Negative Suicide Ideation Inventory - Negative Suicide Ideation (PANSI-NSI)

    Up to 6 weeks

  • Change in Anxiety as Measured Using the Generalized Anxiety Disorder 7-Item (GAD-7) Scale

    Up to 6 weeks

  • Substance Use as Measured by the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST)

    Up to 6 weeks

Study Arms (5)

Enhanced Feedback + Standard Feedback

EXPERIMENTAL

Participants will receive enhanced feedback from the MyDataHelps study app in addition to standard feedback from the activity tracker.

Behavioral: Enhanced Feedback + Standard Feedback

Headspace app + Standard Feedback

EXPERIMENTAL

Participants will receive an app-based intervention in addition to standard feedback from the activity tracker.

Device: Headspace app + Standard Feedback

Headspace app + Enhanced Feedback + Standard Feedback

EXPERIMENTAL

Participants will receive an app-based intervention, enhanced feedback from the MyDataHelps study app, and standard feedback activity tracker.

Device: Headspace app + Enhanced Feedback + Standard Feedback

SilverCloud app + Standard Feedback

EXPERIMENTAL

Participants will receive an app-based intervention in addition to standard feedback from the activity tracker.

Device: SilverCloud + Standard Feedback

SilverCloud app +Enhanced Feedback +Standard Feedback

EXPERIMENTAL

Participants will receive an app-based intervention, enhanced feedback from the MyDataHelps study app, and standard feedback from the activity tracker.

Device: SilverCloud app +Enhanced Feedback +Standard Feedback

Interventions

Standard Feedback (SF) All participants will receive the standard feedback that is standard feedback from the activity trackers. Feedback includes activity level, heart rate, and progress toward daily activity goals on the device itself. Enhanced Feedback (EF) Participants randomized to receive enhanced feedback will receive this feedback from the MyDataHelps study app. This includes varying types of text and visual feedback based on data collected through the app. Feedback will be displayed to participants on a dashboard in the app or delivered via pop-up notifications. Participants will receive a combination of text and visual feedback.

Enhanced Feedback + Standard Feedback

Standard Feedback (SF) All participants will receive the standard feedback that is standard feedback from the activity trackers. Feedback includes activity level, heart rate, and progress toward daily activity goals on the device itself. Headspace is an app designed to train the user in mindfulness practices.

Headspace app + Standard Feedback

Standard Feedback (SF) All participants will receive the standard feedback that is standard feedback from the activity trackers. Feedback includes activity level, heart rate, and progress toward daily activity goals on the device itself. Enhanced Feedback (EF) Participants randomized to receive enhanced feedback will receive this feedback from the MyDataHelps study app. This includes varying types of text and visual feedback based on data collected through the app. Feedback will be displayed to participants on a dashboard in the app or delivered via pop-up notifications. Participants will receive a combination of text and visual feedback. Headspace is an app designed to train the user in mindfulness practices.

Headspace app + Enhanced Feedback + Standard Feedback

Standard Feedback (SF) All participants will receive the standard feedback that is standard feedback from the activity trackers. Feedback includes activity level, heart rate, and progress toward daily activity goals on the device itself. Silvercloud is an app designed to deliver cognitive behavioral therapy.

SilverCloud app + Standard Feedback

Standard Feedback (SF) All participants will receive the standard feedback that is standard feedback from the activity trackers. Feedback includes activity level, heart rate, and progress toward daily activity goals on the device itself. Enhanced Feedback (EF) Participants randomized to receive enhanced feedback will receive this feedback from the MyDataHelps study app. This includes varying types of text and visual feedback based on data collected through the app. Feedback will be displayed to participants on a dashboard in the app or delivered via pop-up notifications. Participants will receive a combination of text and visual feedback. Silvercloud is an app designed to deliver cognitive behavioral therapy.

SilverCloud app +Enhanced Feedback +Standard Feedback

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Must have a scheduled mental health intake appointment at Michigan Medicine Outpatient Psychiatry or University Health Service at the University of Michigan
  • Must have daily access to a smartphone version that is compatible with study activity trackers.
  • Understands English to enable consent and use of the MyDataHelps app and app-based interventions
  • Provide complete, updated contact information upon enrollment to the study
  • Agree to be contacted by study staff during the study
  • Willingness to keep study setup (devices, apps, settings) in required configuration for the duration of the study, and following instructions by study staff if required to update or re-achieve required configuration if required configuration has been lost (e.g., change of phone, app deletion)

You may not qualify if:

  • Self-reported or medical record indication of a current eating disorder
  • Scheduled outpatient mental health appointment is a pediatric appointment (even if age 18+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Michigan

Ann Arbor, Michigan, 48109, United States

Location

Related Publications (1)

  • Horwitz AG, Mills ED, Sen S, Bohnert ASB. Comparative Effectiveness of Three Digital Interventions for Adults Seeking Psychiatric Services: A Randomized Clinical Trial. JAMA Netw Open. 2024 Jul 1;7(7):e2422115. doi: 10.1001/jamanetworkopen.2024.22115.

MeSH Terms

Conditions

DepressionBehavior, AddictiveAnxiety DisordersParasomnias

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorCompulsive BehaviorImpulsive BehaviorMental DisordersSleep Wake DisordersNervous System Diseases

Results Point of Contact

Title
Amy Bohnert
Organization
University of Michigan

Study Officials

  • Amy Bohnert

    University of Michigan

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 8, 2020

First Posted

April 13, 2020

Study Start

May 13, 2020

Primary Completion

February 22, 2023

Study Completion

February 22, 2023

Last Updated

March 17, 2025

Results First Posted

March 17, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations