NCT04327414

Brief Summary

Sitting or sedentary behavior is associated with several adverse health outcomes such as overweight and obesity, diabetes type 2,... independent of physical activity levels. This evidence is clear in adults, however also in adolescents the health effects can become apparent (e.g. development of overweight, reduced fitness,...). Therefore it is important to develop interventions aiming to reduce sedentary behavior in adolescents. Adolescents are sedentary for more than 60% of the day, of wich a large part is spent at school as during school hours pupils usually have to sit at their desk. Therefore secondary schools serve as an ideal setting to target sitting behavior. Structural environmental changes (in the classroom), e.g. introducing standing desks, can be used as a possible strategy. It is important to objectively evaluate the effect of the intervention on sedentary behavior. Next to evaluating the effect on behavior, studies also recommend to evaluate the effect on cognitive performance, as this is the particular interest of schools and their staff. The primary aim of this project is therefore to investigate the effect of implementing standing desks on adolescents' cognitive function, more specifically on memory, reasoning, verbal ability and concentration. In addition, the investigators will evaluate the effect of implementing standing desks on adolescents' sitting and standing time, measured by Axivity accelerometers in the entire sample. Finally, the investigators will also collect information about sleeping behavior to investigate the association with cognitive performance. This will be tested via a controlled trial with a pre- and post-test design including an intervention and control group. Based on previous research studies, the hypothesis is that adolescents from the intervention group will improve their cognitive function and standing time and reduce their sitting time, whereas no changes are expected to be found for adolescents from the control group. Finally, it is expected that a more healthy sleeping behavior is associated with better cognitive performance.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
125

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 10, 2020

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 11, 2020

Completed
20 days until next milestone

First Posted

Study publicly available on registry

March 31, 2020

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 4, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 4, 2020

Completed
Last Updated

January 8, 2021

Status Verified

March 1, 2020

Enrollment Period

10 months

First QC Date

March 11, 2020

Last Update Submit

January 6, 2021

Conditions

Keywords

AdolescentClassroomStanding deskSittingStandingCognitionCognitive functionCognitive performanceSleepSleep qualitySleep duration

Outcome Measures

Primary Outcomes (6)

  • Change in score on the 'Monkey Ladder' task (Cambridge Brain Sciences test battery)

    Task assessing visuospatial working memory

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Change in score on the 'Spatial Span' task (Cambridge Brain Sciences test battery)

    Task assessing spatial short term memory

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Change in score on the 'Token Search' task (Cambridge Brain Sciences test battery)

    Task assessing working memory

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Change in score on the 'Spatial Planning' task (Cambridge Brain Sciences test battery)

    Task assessing planning

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Change in score on the 'Digit Span' task (Cambridge Brain Sciences test battery)

    Task assessing verbal short term memory

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Change in score on the 'Double Trouble' task (Cambridge Brain Sciences test battery)

    Task assessing response inhibition

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

Secondary Outcomes (7)

  • Change in sitting and standing time

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements. The Axivity monitor will be worn during 4 to 5 days.

  • Change in self-reported sitting time at school (included in the questionnaire)

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Change in self-reported number of breaks from sitting time per school hour (included in the questionnaire)

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Change in potential determinants/correlates related to breaking up sitting time (included in the questionnaire)

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • Sleep quality (included in the questionnaire)

    Assessed pre-intervention and immediately after the intervention, with an average of 4 months between both measurements.

  • +2 more secondary outcomes

Study Arms (2)

Intervention group

EXPERIMENTAL

Implementation of standing desks in classroom. To ensure that adolescents will spend sufficient time at the standing desks, 1/3 to half of the classroom will be provided with standing desks. The school will be asked to actually replace some traditional desks with these standing desks, instead of just adding standing desks to the classroom set-up to ensure as much as possible that the desks are being continuously used throughout the intervention period.

Behavioral: Intervention group

Control group

NO INTERVENTION

No implementation of standing desks in classroom.

Interventions

Standing desks

Intervention group

Eligibility Criteria

Age11 Years - 16 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • A 7th or 8th Grade class
  • General secondary education
  • Spending at least 11 lessons hours per week in one classroom

You may not qualify if:

  • Technical or vocational secondary education

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ghent University

Ghent, East Flanders, 9000, Belgium

Location

Related Publications (4)

  • Verloigne M, Ridgers ND, De Bourdeaudhuij I, Cardon G. Effect and process evaluation of implementing standing desks in primary and secondary schools in Belgium: a cluster-randomised controlled trial. Int J Behav Nutr Phys Act. 2018 Sep 27;15(1):94. doi: 10.1186/s12966-018-0726-9.

    PMID: 30261883BACKGROUND
  • Van Oeckel V, Deforche B, Miatton M, Poppe L, Verloigne M. Pupils' and teachers' experiences with implementing standing desks in secondary schools in Belgium. Prev Med Rep. 2025 Oct 21;60:103285. doi: 10.1016/j.pmedr.2025.103285. eCollection 2025 Dec.

  • Van Oeckel V, Poppe L, Deforche B, Brondeel R, Miatton M, Verloigne M. Associations of habitual sedentary time with executive functioning and short-term memory in 7th and 8th grade adolescents. BMC Public Health. 2024 Feb 16;24(1):495. doi: 10.1186/s12889-024-18014-x.

  • Verloigne M, Van Oeckel V, Brondeel R, Poppe L. Bidirectional associations between sedentary time and sleep duration among 12- to 14-year-old adolescents. BMC Public Health. 2021 Sep 15;21(1):1673. doi: 10.1186/s12889-021-11694-9.

MeSH Terms

Conditions

Sedentary BehaviorSleep Initiation and Maintenance Disorders

Condition Hierarchy (Ancestors)

BehaviorSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Study Officials

  • Maïté Verloigne

    University Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Controlled trial: December-January 2020: Recruitment of six secondary schools with immediate allocation to the intervention or control condition and collecting informed consents. February 2020: Pre-test data collection, installing standing desks in intervention schools. March 2020: Interruption of the study due to COVID-19 pandemic. September-October 2020: Recruitment of six new classes and collecting informed consents, pre-test data collection. November-December 2020: Post-test data collection.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 11, 2020

First Posted

March 31, 2020

Study Start

February 10, 2020

Primary Completion

December 4, 2020

Study Completion

December 4, 2020

Last Updated

January 8, 2021

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will share

All IPD that underlie results in a publication.

Time Frame
Will be published together with publication of the article(s).
Access Criteria
Dependent on journal: Probably depositing into data repositories or by publishing the data and files as supplementary information in the journal.

Locations